Artery Research

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Volume 12, Issue C, December 2015, Pages 36 - 36

P8.10 EFFECTS OF BARIATRIC SURGERY ON ENDOTHELIAL FUNCTION IN EXTREMELY OBESE PATIENTS

Authors
Anna Dzieża-Grudnik*, Anna Gαuszewska, Krzysztof Rewiuk, Aleksander Kwater, Bartosz Zarzycki, Maαgorzata Fedyk-Łukasik, Barbara Gryglewska, Tomasz Grodzicki
Department of Internal Medicine and Gerontology, Jagiellonian University, Medical College/University Hospital, Kraków, Poland
Available Online 23 November 2015.
DOI
10.1016/j.artres.2015.10.332How to use a DOI?
Abstract

Introduction: Bariatric surgery in extremely obese patients has influence on metabolic variables and body weight however data about influence on flow-mediated dilatation (FMD) of brachial artery are inconsistent.

The aim of the study was to assess the effect of bariatric surgery on endothelial function measured by flow-mediated dilatation.

Material and methods: We examined 35 patients with extreme obesity who met the eligibility criteria and underwent bariatric surgery (sleeve gastrectomy or Roux-en-Y Bypass).

Brachial flow-mediated dilatation was performed using linear-array transducer (GE Vivid 3, GE Healthcare Medical Diagnostics, Little Chalfont, UK).

Results: Data from 35 patients (34% men; age: 45+/−10) were collected. BMI decreased form 47,5 +/− 6 kg/m2 before surgery to 35,5 +/−5kg/m2 six months after surgery. FMD after six months has significantly improved. Median flow mediated dilatation before intervention was 6,5% (IQR 2–10,7) and after operation 8,5% (IQR 6,2–16,8). Improvement in FMD was higher in patients who underwent by-pass surgery (median 142% (IQR: 85–453)) in comparison to sleeve gastrectomy intervention (median 118% (IQR 67–246) but no statistical significance was observed between two groups.

Conclusions: Bariatric surgery resulted in significant improvement in endothelial function and may have potential impact on reduction of cardiovascular risk.

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<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
12 - C
Pages
36 - 36
Publication Date
2015/11/23
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2015.10.332How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Anna Dzieża-Grudnik*
AU  - Anna Gαuszewska
AU  - Krzysztof Rewiuk
AU  - Aleksander Kwater
AU  - Bartosz Zarzycki
AU  - Maαgorzata Fedyk-Łukasik
AU  - Barbara Gryglewska
AU  - Tomasz Grodzicki
PY  - 2015
DA  - 2015/11/23
TI  - P8.10 EFFECTS OF BARIATRIC SURGERY ON ENDOTHELIAL FUNCTION IN EXTREMELY OBESE PATIENTS
JO  - Artery Research
SP  - 36
EP  - 36
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.332
DO  - 10.1016/j.artres.2015.10.332
ID  - Dzieża-Grudnik*2015
ER  -