Artery Research

Volume 12, Issue C, December 2015, Pages 10 - 11

P3.1 SUB-MAXIMAL EXERCISE BLOOD PRESSURE RELATES TO LEFT VENTRICULAR MASS INDEX, BUT IS DEPENDENT ON LOW AEROBIC CAPACITY

Authors
Martin Schultz*1, Dean Picone1, Rachel Climie1, Costan Magnussen1, 2, Leah Wright1, Thomas Marwick1, Alison Venn1, James Sharman1
1Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
2Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland
Available Online 23 November 2015.
DOI
10.1016/j.artres.2015.10.226How to use a DOI?
Abstract

Background: Exaggerated blood pressure (BP) responses to sub-maximal exercise independently predict cardiovascular (CV) events, mortality and incident hypertension. The aim of this study was to explore relationships between exercise BP, left-ventricular (LV) structure and function and aerobic fitness as potential mechanisms underlying the CV risk associated with sub-maximal exercise BP.

Methods: 149 participants aged 40±2 years, 45% male completed a staged cycle test to estimate physical work capacity (aerobic fitness; PWC170) with concomitant BP measured each two minutes. 2D echocardiography was used to quantify LV mass (obtained from 2D-guided M-mode echo), and LV function (longitudinal strain, haemodynamics).

Results: Early-stage exercise systolic BP was associated with aerobic fitness and LV mass index (r=0.22, and 0.24, p<0.05) and was greater in those performing high stage-relative work (high-fitness) compared with low stage-relative work (low-fitness) (154±22 vs. 133±15 mmHg, p<0.001). The high-fitness group had greater stroke volume, lower heart rate and LV longitudinal strain compared to the low-fitness group (72±18 vs. 59±15 ml, 61±9 vs. 68±9 bpm, −18±4 vs. −20±3%, p<0.05 for all). Exercise systolic BP was associated with LV mass index independent of resting BP, age and sex in the low-fitness group during stage one of the PWC170 (β=0.13, 95% CI=0.01-0.3) but not in the high-fitness group at any stage.

Conclusions: Sub-maximal exercise systolic BP independently relates to LV mass index in those with low, early stage-relative aerobic capacity. BP measured during submaximal exercise testing (light-intensity) may reveal early changes in hypertension-related organ damage that are more evident in people with low-fitness.

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Journal
Artery Research
Volume-Issue
12 - C
Pages
10 - 11
Publication Date
2015/11/23
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2015.10.226How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Martin Schultz*
AU  - Dean Picone
AU  - Rachel Climie
AU  - Costan Magnussen
AU  - Leah Wright
AU  - Thomas Marwick
AU  - Alison Venn
AU  - James Sharman
PY  - 2015
DA  - 2015/11/23
TI  - P3.1 SUB-MAXIMAL EXERCISE BLOOD PRESSURE RELATES TO LEFT VENTRICULAR MASS INDEX, BUT IS DEPENDENT ON LOW AEROBIC CAPACITY
JO  - Artery Research
SP  - 10
EP  - 11
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.226
DO  - 10.1016/j.artres.2015.10.226
ID  - Schultz*2015
ER  -