P2.18 IMPACT OF CARDIOVASCULAR RISK FACTORS ON CAROTID STIFFNESS AND CAROTID INTIMA MEDIA THICKNESS – GENDER DIFFERENCES

Maria Loboz-Rudnicka*; Joanna Jaroch; Zbigniew Bociaga; Barbara Rzyczkowska; Ewa Kruszynska; Krystyna Loboz-Grudzien; Andrzej Szuba

doi:10.1016/j.artres.2015.10.223

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Volume 12, Issue C, December 2015, Pages 10 - 10

P2.18 IMPACT OF CARDIOVASCULAR RISK FACTORS ON CAROTID STIFFNESS AND CAROTID INTIMA MEDIA THICKNESS – GENDER DIFFERENCES

Authors

Maria Loboz-Rudnicka*¹, Joanna Jaroch¹, Zbigniew Bociaga¹, Barbara Rzyczkowska¹, Ewa Kruszynska¹, Krystyna Loboz-Grudzien¹^{, 2}, Andrzej Szuba³

¹Departemnt of Cardiology, T. Marciniak Hospital, Wroclaw, Poland

²Faculty of Health Science, Medical University of Wroclaw, Wroclaw, Poland

³Department of Internal Medicine, 4th Military Hospital in Wroclaw, Wroclaw, Poland

Available Online 23 November 2015.

DOI: 10.1016/j.artres.2015.10.223 How to use a DOI?
Abstract: Background and purpose: Whether the influence of risk factors on carotid stiffness (CS) and carotid intima media thickness (CIMT) is modulated by gender is still unclear. The aim of our study was to examine the association between cardiovascular (CV) risk factors, CS and CIMT in men and women.

Material and methods: 252 subjects (including 132 women), mean age: 55 years, with CV risk factors and without the history of manifest CV disease underwent the examination of CS parameters and CIMT. The following CS parameters: beta stiffness index (beta), Peterson’s elastic modulus (Ep), one-point pulse wave velocity (PWV-beta) and arterial compliance (AC) were measured with the use of the high-resolution echotracking system.

Results: The multivariate analysis revealed that age, diabetes and MAP were independent determinants of CS parameters in both men and women. Pulse pressure (PP) was significantly associated with beta (β coefficient +0,261, p=0,006), Ep (β coefficient +0,426, p<0,001) and PWV-beta (β coefficient +0,283, p=0,007) only in women. Of the risk factors significantly associated with CIMT in the multivariate analysis, age was an independent determinant of CIMT in both sexes, while PP (β coefficient +0,317, p=0,014) and increased waist circumference (β coefficient +0,207, p=0,048) only in women.

Conclusions: The influence of CV risk factors on CS and CIMT is modulated by gender. The impact of the pulsatile component of blood pressure on CS and CIMT and of the increased waist circumference on CIMT seems to be more prominent in women than in men.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 12 - C
Pages: 10 - 10
Publication Date: 2015/11/23
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2015.10.223 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - Maria Loboz-Rudnicka*
AU  - Joanna Jaroch
AU  - Zbigniew Bociaga
AU  - Barbara Rzyczkowska
AU  - Ewa Kruszynska
AU  - Krystyna Loboz-Grudzien
AU  - Andrzej Szuba
PY  - 2015
DA  - 2015/11/23
TI  - P2.18 IMPACT OF CARDIOVASCULAR RISK FACTORS ON CAROTID STIFFNESS AND CAROTID INTIMA MEDIA THICKNESS – GENDER DIFFERENCES
JO  - Artery Research
SP  - 10
EP  - 10
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.223
DO  - 10.1016/j.artres.2015.10.223
ID  - Loboz-Rudnicka*2015
ER  -

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