Artery Research

Volume 20, Issue C, December 2017, Pages 92 - 92

P110 DIFFERENCES IN ARTERIAL STIFFNESS MEASURED BY CARDIO-ANKLE VASCULAR INDEX IN PATIENTS WITH NORMAL AND DECREASED RENAL FUNCTION

Authors
Marius Miglinas1, Alvita Gincaite1, Laurynas Rimsevicius1, Ligita Ryliskyte2, Jolita Badariene2, Aleksandras Laucevicius2
1Clinic of Gastroenterology, Nephrourology and Surgery, Faculty of Medicine, Vilnius University, Lithuania
2Centre of Cardiology and Angiology, Faculty of Medicine, Vilnius University, Lithuania
Available Online 6 December 2017.
DOI
10.1016/j.artres.2017.10.141How to use a DOI?
Abstract

Background: Arterial stiffness (AS) is a highly prognostic risk factor of cardiovascular diseases. The aim of this study was to investigate the relationships between cardio-ankle vascular index (CAVI) and eGFR in patients under the risk of cardiovascular disease.

Methods: This was a retrospective study of Lithuania High cardiovascular risk patients’ database. Demographic, renal function and AS data was gathered. Patients were divided into groups by gender and age by intervals of 5 years. Mean values of CAVI were further investigated according to the patients’ eGFR. ANOVA was used to compare mean values of CAVI.

Results: This study included data of 2070 patients aged from 40 to 65 years. The mean eGFR of the patients was 100.13 ml/min/1.73m2, 58.7% were women. The increase in CAVI was observed with age in overall population, with mean values in different age groups of 6.55±1.28, 7.13±1.84, 7.71±1.92, 7.79±1.95, 7.73±1.98, 8.06±1.79, p < 0.001. Calculation of the mean CAVI in different age and gender groups of eGFR are presented in Table 1. Further comparison of mean values of CAVI did not yield statistically significant results.

eGFR Men Women


40–5 p 45–0 p 50–5 p 50–5 p 55–0 P 60–5 p
<60 5,80 0,159 8,58 0,610 7,74 0,150 7,70 0,948 6,34 0,172 7,33 0,068
60–90 6,63 7,80 7,71 7,54 7,73 8,23
>90 7,17 7,67 8,32 7,49 7,78 7,92
Table 1.

Mean values of CAVI.

Conclusions: Arterial stiffness increases with age in overall population. There was no statistically significant difference between mean values of CAVI in groups divided by age and gender according to eGFR.

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Journal
Artery Research
Volume-Issue
20 - C
Pages
92 - 92
Publication Date
2017/12/06
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2017.10.141How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Marius Miglinas
AU  - Alvita Gincaite
AU  - Laurynas Rimsevicius
AU  - Ligita Ryliskyte
AU  - Jolita Badariene
AU  - Aleksandras Laucevicius
PY  - 2017
DA  - 2017/12/06
TI  - P110 DIFFERENCES IN ARTERIAL STIFFNESS MEASURED BY CARDIO-ANKLE VASCULAR INDEX IN PATIENTS WITH NORMAL AND DECREASED RENAL FUNCTION
JO  - Artery Research
SP  - 92
EP  - 92
VL  - 20
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2017.10.141
DO  - 10.1016/j.artres.2017.10.141
ID  - Miglinas2017
ER  -