Artery Research

Volume 20, Issue C, December 2017, Pages 89 - 89

P99 THE EFFECT OF L-ARGININE ON THE VASCULAR FUNCTION IN HEALTHY TRAINED AND SEDENTARY SUBJECTS

Authors
Ksenija Cankar, Tina Virtič, Polona Zaletel, Ziva Melik
University of Ljubljana, Faculty of Medicine, Institute of Physiology, Slovenia
Available Online 6 December 2017.
DOI
10.1016/j.artres.2017.10.135How to use a DOI?
Abstract

Background: The aim of our study was to determine whether the use of food supplement L-arginine improves vascular function, which could be beneficial in preventing the formation and development of cardiovascular diseases. We investigated differences between trained and sedentary subjects.

Method: Measurements were performed in healthy normotensive men, divided into four groups, according to age and physical activity: 12 young sedentary (YS) (mean age 23,5±2,4) and age matched trained (YT) (N = 18); 11 elder sedentary (ES) (mean age 45,7±7,5) and age matched trained (ET) (N = 12) subjects. Parameters were measured at rest with the Task Force Monitor device (CNSystems Medizintechnik, Austria) before and after administration of 0.9 g L-arginine.

Results: After ingestion of L-arginine the heart rate in all groups statistically significantly decreased (YS 70.4±4.2 vs. 66.3±3.3; YT 62.1±2.7 vs. 58.3±2.0; ES 69.6±3.2 vs. 62.7±2.7; ET 58.0±1.8 vs. 53.6±1.2 beats/min) (paired t-test, p < 0.05). The cardiac output decreased in three groups (YT 7.04±0.4 vs. 6.32±0.3; ES 6.95±0.5 vs. 5.9±0.4; ET 7.08±0.6 vs. 6.58±0.4 L/min) (paired t-test, p < 0.05). The systolic (126.3±4.1 vs. 120.0±3.2 mmHg) and diastolic pressure (77.6±2.5 vs. 74.3±1.9 mmHg) (paired t-test, p < 0.05) decreased in the ES group.

Conclusions: The systemic effect of L-arginine was observed. Improved cardiovascular function in response to L-arginine could justify the use of dietary L-arginine supplementation.

Open Access
This is an open access article distributed under the CC BY-NC license.

Journal
Artery Research
Volume-Issue
20 - C
Pages
89 - 89
Publication Date
2017/12/06
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2017.10.135How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Ksenija Cankar
AU  - Tina Virtič
AU  - Polona Zaletel
AU  - Ziva Melik
PY  - 2017
DA  - 2017/12/06
TI  - P99 THE EFFECT OF L-ARGININE ON THE VASCULAR FUNCTION IN HEALTHY TRAINED AND SEDENTARY SUBJECTS
JO  - Artery Research
SP  - 89
EP  - 89
VL  - 20
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2017.10.135
DO  - 10.1016/j.artres.2017.10.135
ID  - Cankar2017
ER  -