Artery Research

Volume 1, Issue 2, September 2007, Pages 52 - 52

10.03 EARLY REFLECTION OBSERVED IN THE PULSE WAVE IN THE COMMON CAROTID ARTERY ORIGINATES FROM EITHER THE CIRCLE OF WILLIS OR THE CAPILLARY BED OF THE FACIAL MUSCULATURE

Authors
E. Hermeling, K.D. Reesink, A.P. Hoeks
Dept. of Biophysics/Biomedical engineering, Cardiovascular Reseach Institute Maastricht, Maastricht Univesity, Maastricht, Limburg, Netherlands
Available Online 30 August 2007.
DOI
10.1016/j.artres.2007.07.056How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Introduction: Arterial wave reflections augment pulse pressures at heart level and manifest as an inflection point in the blood pressure waveform. However, the origin of reflection is still partly unresolved and can not be derived using the waveform from a single location.

Method: Two distension waveforms, spaced at 16.4mm, were simultaneously obtained in the left CCA of 12 young subjects with dual M-line ultrasound. The second derivatives of the distension waveforms were calculated to identify the opening of the aortic valve (AVO) and the inflection point before systolic peak pressure (IP). The time-delay (ΔT) between both time points, either AVO or IP, in the proximal and distal waveform was calculated to obtain the direction of propagation.

Results: Mean time difference between AVO and IP was 38 ± 8ms. There was a significant time difference in AVO (p<0.0001) and IP (p=0.0012) between proximal and distal waveform. AVO had a positive delay ΔTAvO=3.3 ± 1.0ms. In contrast IP had a negative delay ΔTIP=−3.6 ± 3.1ms.

Discussion: Time-delay of AVO and IP are comparable but opposite in sign. Measurements were performed on the CCA, which is a small straight arterial segment without branches, therefore the effect of dispersion or tapering can be ignored and the direction of propagation of IP can only be explained by reflections. Using the time difference between AVO and IP and assuming constant wave-speed, the distance between reflection and measurement site was estimated at 12cm, pointing at the circle of Willis or the capillary bed of the facial musculature as distal reflection sites.

Journal
Artery Research
Volume-Issue
1 - 2
Pages
52 - 52
Publication Date
2007/08/30
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2007.07.056How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - E. Hermeling
AU  - K.D. Reesink
AU  - A.P. Hoeks
PY  - 2007
DA  - 2007/08/30
TI  - 10.03 EARLY REFLECTION OBSERVED IN THE PULSE WAVE IN THE COMMON CAROTID ARTERY ORIGINATES FROM EITHER THE CIRCLE OF WILLIS OR THE CAPILLARY BED OF THE FACIAL MUSCULATURE
JO  - Artery Research
SP  - 52
EP  - 52
VL  - 1
IS  - 2
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2007.07.056
DO  - 10.1016/j.artres.2007.07.056
ID  - Hermeling2007
ER  -