Artery Research

Volume 1, Issue 2, September 2007, Pages 55 - 55

P.013 BLOOD PRESSURE, ARTERIAL RIGIDITY AND ALCOHOL INTAKE IN A POPULATION SAMPLE☆

Authors
O. Mayer, J. Filipovský, M. Dolejšová, L. Handl
2nd Dept. of Internal Medicine, Charles University, Medical Faculty, Pilsen, Czech Republic

(supported by Internal Grant Agency, Ministry of Health CZ, grant No 9333-3).

Available Online 30 August 2007.
DOI
10.1016/j.artres.2007.07.070How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Objectives: Increased alcohol intake impaires the control of hypertension in treated patients. The aim of this study was to evaluate the relation between weekly alcohol intake, blood pressure and arterial stiffness.

Methods: 257 subjects (m126, f131 mean age 48.04 ± 0.66) were selected from population- based postMONICA study. Arterial stiffness was measured using Sphygmocor device as aortic pulse wave velocity (APWV) and radial augmentation index (RAIx), the one-week alcohol intake was ascertained by diet recall.

Results: The sample was divided according to reported weekly intake of pure alcohol into 3 categories: none or minimal intake (0–42g), mild drinkers (43–154 g) and moderate to heavy drinkers (> 154g). Among these categories, significant increasing trend in blood pressure and aortic rigidity were found (see table). These trends remained significant even after adjustment for age, current smoking, body mass index, antihypertensive treatment, LDL and glyceamia as potentially confounding factors of hypertension and/or increased arterial rigidity.

weekly alcohol intake: 0–42g 43–154 g >154 g p for trend
N 131 72 54 -
age [years] 47.9 ± 0.99 48.3 ± 1.30 48.1 ± 1.45 0.83
gender [% of males] 21.4 65.3 94.4 <0.0001
body mass index [kg/m2] 26.1 ± 0.36 26.9 ± 0.45 27.2 ± 0.56 0.14
systolic BP [mmHg] 122.8 ± 1.46 128.0 ± 2.03 130.3 ± 1.77 <0.003
diastolic BP [mmHg] 78.2 ± 0.88 82.0 ± 1.43 83.1 ± 1.28 <0.03
antihypertensives [%] 18.3 23.6 13.0 0.31
APWV [m/sec] 7.36 ± 0.18 7.44 ± 0.24 8.24 ± 0.46 <0.02
RAIx [%] 73.8 ± 1.89 71.2 ± 2.51 66.9 ± 2.99 0.35

Conclusion: Moderate to heavy drinkers showed in our general population sample gradually higher blood pressure, probably because of increased aortic stiffness.

Journal
Artery Research
Volume-Issue
1 - 2
Pages
55 - 55
Publication Date
2007/08/30
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2007.07.070How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - O. Mayer
AU  - J. Filipovský
AU  - M. Dolejšová
AU  - L. Handl
PY  - 2007
DA  - 2007/08/30
TI  - P.013 BLOOD PRESSURE, ARTERIAL RIGIDITY AND ALCOHOL INTAKE IN A POPULATION SAMPLE☆
JO  - Artery Research
SP  - 55
EP  - 55
VL  - 1
IS  - 2
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2007.07.070
DO  - 10.1016/j.artres.2007.07.070
ID  - Mayer2007
ER  -