Artery Research

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Volume 3, Issue 4, December 2009, Pages 156 - 156

5.4 THE REPEATABILITY AND VALIDITY OF PULSE WAVE VELOCITY MEASURED USING PHASE CONTRAST MAGNETIC RESONANCE IMAGING

Authors
S.S. Hickson1, M. Butlin2, M. Graves1, I.B. Wilkinson1, C.M. McEniery1
1University of Cambridge, Cambridge, United Kingdom
2Macquarie University, Sydney, Australia
Available Online 3 December 2009.
DOI
10.1016/j.artres.2009.10.162How to use a DOI?
Abstract

Background: Aortic pulse wave velocity (PWV) is an independent predictor of cardiovascular risk. Phase contrast magnetic resonance imaging (PCMRI) is a recent technique that allows PWV to be measured along the entire aorta (aPWVMRI), as well as in regions of interest. The aim of this study was to test the repeatability of PWV assessed by MRI, and to validate this against carotid-femoral PWV using the Vicorder device (PWVVicorder) measured simultaneously to aPWVMRI.

Methods: 147 subjects aged 18–85 years were recruited from the ACCT and ENIGMA Studies. All subjects were free of cardiovascular disease and medication. A PCMRI sequence (1.5T scanner, GE) was performed at two sites (1cm above the aortic valve, and 3cm above the aortic bifurcation) to determine aPWVMRI. Brachial supine blood pressure and PWVVicorder were measured in the scanner simultaneous to image acquisition. Repeatability of PWVMRI was assessed across 2 visits, in a subset of 10 subjects.

Results: PWVMRI showed good repeatability (mean difference = −0.4±2.1m/s). There was a strong correlation between aPWVMRI and PWVVicorder (R=0.64, P<0.001), although, overall, aPWVMRI was significantly lower than PWVVicorder (5.7±1.8 vs. 7.1±1.4m/s, P<0.001).

Conclusions: Measurements of PWV using PCMRI are reproducible and correlate with simultaneously measured carotid-femoral PWV.

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<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
3 - 4
Pages
156 - 156
Publication Date
2009/12/03
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2009.10.162How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - S.S. Hickson
AU  - M. Butlin
AU  - M. Graves
AU  - I.B. Wilkinson
AU  - C.M. McEniery
PY  - 2009
DA  - 2009/12/03
TI  - 5.4 THE REPEATABILITY AND VALIDITY OF PULSE WAVE VELOCITY MEASURED USING PHASE CONTRAST MAGNETIC RESONANCE IMAGING
JO  - Artery Research
SP  - 156
EP  - 156
VL  - 3
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2009.10.162
DO  - 10.1016/j.artres.2009.10.162
ID  - Hickson2009
ER  -