Artery Research

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Volume 3, Issue 4, December 2009, Pages 178 - 178

P2.07 MASKED HYPERTENSION IS “UNMASKED” BY LOW INTENSITY EXERCISE BLOOD PRESSURE

Authors
M.G. Schultz2, M. Stowasser2, J.L. Hare2, T.H. Marwick2, J.E. Sharman1
1Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
2University of Queensland, Department of Medicine, Brisbane, Queensland, Australia
Available Online 3 December 2009.
DOI
10.1016/j.artres.2009.10.023How to use a DOI?
Abstract

Background: Masked hypertension (MH) independently predicts mortality but cannot be diagnosed from clinic blood pressure (BP). We sought to determine if MH could be identified from BP or pressure waveform analysis (PWA) at rest or during low intensity exercise.

Methodology: Brachial and estimated central BP (by PWA; SphygmoCor) were recorded at rest and during ≈10minutes of cycling exercise (60–70% of age-predicted maximal heart rate) in 77 untreated subjects with a hypertensive response to exercise (HRE) (aged 54±8years) and 61 patients with hypertension (HT) receiving therapy (aged 62±8years). All subjects underwent 24hour ambulatory BP monitoring (24hrABPM) and MH was defined as clinic systolic BP (SBP) <140mmHg and 24ABPM SBP ≥130mmHg.

Results: There were 44 (57%) HRE and 32 (52%) HT patients with MH. For the HRE group at rest, there were no significant differences between MH and normotensive subjects in any haemodynamic variable except brachial systolic BP, which was higher in MH subjects (127±9 vs. 120±9mmHg; p<0.05). After correction for resting SBP, MH subjects had significantly higher brachial (187±22 vs. 168±15mmHg; p<0.05) and central SBP (154±17 vs. 141±12mmHg; p<0.05) during exercise, with greater changes in both from baseline (p<0.05). No differences were observed in the HT group. Exercise brachial SBP predicted the presence of MH independent from all resting hemodynamic variables (β=0.35; p<0.001), and if >190mmHg, identified MH with 97% specificity (p<0.001).

Conclusions: MH can be identified in untreated individuals from low intensity exercise brachial SBP. Exercise BP testing may be indicated in patients with borderline raised clinic brachial SBP.

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This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
3 - 4
Pages
178 - 178
Publication Date
2009/12/03
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2009.10.023How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - M.G. Schultz
AU  - M. Stowasser
AU  - J.L. Hare
AU  - T.H. Marwick
AU  - J.E. Sharman
PY  - 2009
DA  - 2009/12/03
TI  - P2.07 MASKED HYPERTENSION IS “UNMASKED” BY LOW INTENSITY EXERCISE BLOOD PRESSURE
JO  - Artery Research
SP  - 178
EP  - 178
VL  - 3
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2009.10.023
DO  - 10.1016/j.artres.2009.10.023
ID  - Schultz2009
ER  -