Artery Research

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Volume 13, Issue C, March 2016, Pages 1 - 5

A pilot study of scanning acoustic microscopy as a tool for measuring arterial stiffness in aortic biopsies

Authors
Riaz Akhtara, *, J. Kennedy Cruickshankb, Xuegen Zhaoc, Brian Derbyc, Thomas Weberd
aCentre for Materials and Structures, School of Engineering, University of Liverpool, L69 3GH, UK
bDiabetes & Cardiovascular Medicine, Nutritional Sciences Division, King’s College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
cSchool of Materials, The University of Manchester, Manchester M13 9PL, UK
dCardiology Department, Klinikum Wels-Grieskirchen, Grieskirchnerstrasse 42, 4600 Wels, Austria
*Corresponding author. Tel.: +44 151 794 5770. E-mail address: r.akhtar@liverpool.ac.uk (R. Akhtar).
Corresponding Author
Riaz Akhtar
Received 19 September 2015, Revised 2 November 2015, Accepted 9 November 2015, Available Online 12 December 2015.
DOI
10.1016/j.artres.2015.11.001How to use a DOI?
Keywords
Arterial stiffening; Scanning acoustic microscopy; Cholesterol; Glucose; Blood pressure; Pulse wave velocity; Acoustic wave speed
Abstract

This study explores the use of scanning acoustic microscopy (SAM) as a potential tool for characterisation of arterial stiffness using aortic biopsies. SAM data is presented for human tissue collected during aortic bypass graft surgery for multi-vessel coronary artery disease. Acoustic wave speed as determined by SAM was compared to clinical data for the patients namely, pulse wave velocity (PWV), blood pressure, cholesterol and glucose levels. There was no obvious trend relating acoustic wave speed to PWV values, and an inverse relationship was found between systolic and diastolic blood pressure and acoustic wave speed. However, in patients with a higher cholesterol or glucose level, the acoustic wave speed increased. A more detailed investigation is needed to relate SAM data to clinical measurements.

Copyright
© 2015 The Authors. Published by Elsevier Ltd.
Open Access
This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Next Article In Issue>
Journal
Artery Research
Volume-Issue
13 - C
Pages
1 - 5
Publication Date
2015/12/12
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2015.11.001How to use a DOI?
Copyright
© 2015 The Authors. Published by Elsevier Ltd.
Open Access
This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Cite this article

risenwbib
TY  - JOUR
AU  - Riaz Akhtar
AU  - J. Kennedy Cruickshank
AU  - Xuegen Zhao
AU  - Brian Derby
AU  - Thomas Weber
PY  - 2015
DA  - 2015/12/12
TI  - A pilot study of scanning acoustic microscopy as a tool for measuring arterial stiffness in aortic biopsies
JO  - Artery Research
SP  - 1
EP  - 5
VL  - 13
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.11.001
DO  - 10.1016/j.artres.2015.11.001
ID  - Akhtar2015
ER  -