The effects of pipe water smoking on endothelial function in healthy non smoker volunteers
- https://doi.org/10.1016/j.artres.2016.05.001How to use a DOI?
- Pipe water smoking, Endothelial dysfunction, FMD%
Background: Water pipe (WP) tobacco smoking is gaining wide popularity among young and middle aged males and females.
Aim of the work: The aim of this study was to evaluate the immediate effect of 1st pipe water smoking on brachial Flow mediated dilatation% (FMD%) and Nitrate mediated dilatation% (NMD%) as markers of systemic endothelial function.
Methods: The present study comprised of 40 young healthy volunteers with no cardiovascular risk factors (the mean age 28 ± 5 years, males) randomized to either smoking (cigarette or pipe water) or not smoking in a crossover fashion. All the participants underwent a physical examination, laboratory analysis, Standard echocardiography, brachial artery FMD% = [(Dmax–Dbase)/Dbase] multiplied by 100 (%). and endothelium independent dilation (NMD%) = [(DNTG-Dbase)/Dbase] multiplied by 100 (%) were assessed with a high-resolution ultrasound probe and the arterial diameters before smoking, just after smoking, 1 h and 2 h after obtained.
Results: FMD% after 1 h of both water pipe and cigarette were significantly lower (p < 0.001) than FMD% of the base – line and normalized after 2 h. No differences in median NMD % values (p > 0.05).
Conclusion: Our findings confirm that even one time pipe water smoking is associated with systemic endothelial dysfunction comparable to cigarette smoking in young non-smoker volunteers with no cardiovascular disorders or risk factors.
- © 2016 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - JOUR AU - Rania Gaber AU - Manal Hamesa PY - 2016 DA - 2016/05 TI - The effects of pipe water smoking on endothelial function in healthy non smoker volunteers JO - Artery Research SP - 1 EP - 5 VL - 15 IS - C SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2016.05.001 DO - https://doi.org/10.1016/j.artres.2016.05.001 ID - Gaber2016 ER -