Aggressive renal sympathetic denervation approach to treating resistant hypertension: A fresh start?

Márcio Galindo Kiuchi; Luis Marcelo Rodrigues Paz; Shaojie Chen

doi:10.1016/j.artres.2016.10.143

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Volume 16, Issue C, December 2016, Pages 42 - 44

Aggressive renal sympathetic denervation approach to treating resistant hypertension: A fresh start?

Authors

Márcio Galindo Kiuchi^a^{, b}^{, *}, Luis Marcelo Rodrigues Paz^a, Shaojie Chen^c

^aDivision of Cardiac Surgery and Artificial Cardiac Stimulation, Department of Medicine, Hospital e Clínica São Gonçalo, São Gonçalo, RJ, Brazil

^bElectrophysiology Division, Department of Cardiology, Hospital e Clínica São Gonçalo, São Gonçalo, RJ, Brazil

^cDepartment of Cardiology, Shanghai First People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

^*Corresponding author. Rua Cel. Moreira César, 138 – Centro, São Gonçalo, Rio de Janeiro, 24440-400, Brazil. Fax: +55 21 26047744. E-mail address: marciokiuchi@gmail.com (M.G. Kiuchi).

Corresponding Author

Márcio Galindo Kiuchi

Received 10 August 2016, Accepted 19 October 2016, Available Online 1 November 2016.

DOI: 10.1016/j.artres.2016.10.143 How to use a DOI?
Keywords: Resistant hypertension; Renal sympathetic denervation; Blood pressure
Abstract: A multivariable analysis identified predictors of systolic blood pressure change in SYMPLICITY HTN-3 trial. Additional analyses examined the influence of medication changes, results in selected subgroups and procedural factors. Greater reductions in office and ambulatory systolic blood pressure, and heart rate were observed with a higher number of ablations and energy delivery in a four-quadrant pattern. Based on this information, we selected a white patient with baseline office systolic blood pressure >180 mmHg, using aldosterone antagonist, non-using vasodilators, and performed an aggressive RSD approach.

Male patient, 40 years old, white, referred by the attending physician to our service due to a complaint of dyspnea, dizziness, and headache. Resistant hypertensive patient, already being tested various therapeutic regimens. The procedure did not show any vascular complications and the patient was discharged after 24 h hospitalization, clinically stable, walking without difficulty, and presenting mean office blood pressure levels during the 24 h post procedure in 130/82 mmHg. After 6 months of follow-up, the office blood pressure was 140/89 mmHg, and the 24-h ABPM values were: mean = 132/83 mmHg, awake = 135/86 mmHg, and sleeping = 126/75 mmHg, and did not present any symptoms.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 16 - C
Pages: 42 - 44
Publication Date: 2016/11/01
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2016.10.143 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - Márcio Galindo Kiuchi
AU  - Luis Marcelo Rodrigues Paz
AU  - Shaojie Chen
PY  - 2016
DA  - 2016/11/01
TI  - Aggressive renal sympathetic denervation approach to treating resistant hypertension: A fresh start?
JO  - Artery Research
SP  - 42
EP  - 44
VL  - 16
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2016.10.143
DO  - 10.1016/j.artres.2016.10.143
ID  - Kiuchi2016
ER  -

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