Artery Research

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Volume 16, Issue C, December 2016, Pages 18 - 24

Estimates of arterial stiffness and central blood pressure in patients with type 2 diabetes: A comparison of SphygmoCor and Arteriograph

Authors
Christoffer Krogagera, b, d, *, Niklas B. Rossena, b, Klavs W. Hansenb, Søren T. Knudsena, Christian D. Peterse, Hans Erik Bøtkerf, Per L. Poulsena, Esben Laugesena, c, d
aDepartment of Endocrinology and Internal Medicine, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus, Denmark
bDiagnostic Centre, Regional Hospital Silkeborg, Falkevej 3, 8600 Silkeborg, Denmark
cDepartment of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 82, 8200 Aarhus N, Denmark
dThe Danish Diabetes Academy, Odense University Hospital, Sdr Boulevard 29, 5000 Odense C, Denmark
eDepartment of Renal Medicine, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark
fDepartment of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark
*Corresponding author. Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark. Fax: +45 78462150. E-mail address: ck@clin.au.dk (C. Krogager).
Corresponding Author
Christoffer Krogager
Received 21 June 2016, Revised 18 July 2016, Accepted 24 August 2016, Available Online 24 September 2016.
DOI
10.1016/j.artres.2016.08.041How to use a DOI?
Keywords
Arterial stiffness; Augmentation index; Central blood pressure; Diabetes; SphygmoCor; Arteriograph; Reproducibility
Abstract

Background: The Arteriograph is a cuff-based oscillometric device for non-invasive assessment of central systolic blood pressure (cSBP), aortic augmentation index (Aix) and aortic pulse wave velocity (PWV). Reproducibility of Arteriograph measurements and the agreement with SphygmoCor in diabetic patients has never been assessed.

Methods: We compared Arteriograph reproducibility and agreement with SphygmoCor with data from two study populations: Study 1 (n = 17) was conducted in a research laboratory and Study 2 (n = 19) in a catheter lab. SphygmoCor PWV data was only available in study 1.

Results: Reproducibility: Mean differences (±Standard deviation of the difference (SDD)) between duplicate cSBP, Aix and PWV Arteriograph measurements were −0.6 ± 6.6 mmHg, −1.1 ± 3.3% and 0.1 ± 0.5 m/s in study 1 and −0.01 ± 4.3 mmHg, 1.5 ± 3.2% and −0.2 ± 0.6 m/s in study 2, all differences non-significant. Agreement: Mean differences between SphygmoCor and Arteriograph were −14 ± 10 mmHg, −8 ± 7% and 2.4 ± 1.8 m/s, (p < 0.001 for all) in Study 1 and −5 ± 10 mmHg, p = 0.04 and −10 ± 8%, p = <0.001 in Study 2. In study 1, a significant correlation was observed between the mean and the difference for cSBP, r = −0.75, p < 0.001 and for Aix, r = −0.67, p < 0.001.

Conclusions: In type 2 diabetics, Arteriograph data were reproducible yet systematically overestimated cSBP, Aix and PWV compared with SphygmoCor. Hence, the two devices cannot be used interchangeably in type 2 diabetics.

Copyright
© 2016 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

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<Previous Article In Issue
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Journal
Artery Research
Volume-Issue
16 - C
Pages
18 - 24
Publication Date
2016/09/24
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2016.08.041How to use a DOI?
Copyright
© 2016 Association for Research into Arterial Structure and Physiology. Published by Elsevier B.V. All rights reserved.
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Christoffer Krogager
AU  - Niklas B. Rossen
AU  - Klavs W. Hansen
AU  - Søren T. Knudsen
AU  - Christian D. Peters
AU  - Hans Erik Bøtker
AU  - Per L. Poulsen
AU  - Esben Laugesen
PY  - 2016
DA  - 2016/09/24
TI  - Estimates of arterial stiffness and central blood pressure in patients with type 2 diabetes: A comparison of SphygmoCor and Arteriograph
JO  - Artery Research
SP  - 18
EP  - 24
VL  - 16
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2016.08.041
DO  - 10.1016/j.artres.2016.08.041
ID  - Krogager2016
ER  -