Proceedings of the Third International Conference on Social Science, Public Health and Education (SSPHE 2019)

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The Role of Cystatin C and Albumin in the Differential Diagnosis of Primary Chronic Glomerulonephritis and Hypertension-Induced Renal Injury

Authors
Shen Li, Changle Zhang, Ke Zhang, Jumin Song
Corresponding Author
Shen Li
Available Online 13 February 2020.
DOI
10.2991/assehr.k.200205.025How to use a DOI?
Keywords
primary chronic glomerulonephritis, Hypertension-induced renal injury, Cystatin C, Albumin
Abstract

Background: It was difficult to differentiate diseases in patients of Primary chronic glomerulonephritis (PCG) and Hypertension-induced renal injury (HRI). This study aimed to investigate the role of serum Cystatin C and Albumin in differential diagnosis of PCG and HRI. Materials and Methods: A total of 150 patients (79 PCG and 71 HRI) considering for our clinic between October 2017 and August 2018 were included. Patients were included in the study newly diagnosed by biopsy. Urinary samples and blood samples were collected and measured. The diagnostic roles were investigated using the receiver operator curve curves. Results: There was an increased serum levels of Albumin in patients with PCG compared with that in patients with HRI. Patients with HRI had a significantly increased serum levels of Cystatin C than those with PCG. An Albumin level of 2.295 g/L had an 80.3% sensitivity and a 73.4% specificity, Cystatin C level of 36.200 mg/L had a 79.7% sensitivity and a 93% specificity for differential diagnosis of PCG and HRI. Conclusions: Serum Cystatin C and Albumin level might be used as tool to differentiate PCG from HRI. Further studies are needed to confirm the definite the role of those markers.

Copyright
© 2020, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the Third International Conference on Social Science, Public Health and Education (SSPHE 2019)
Series
Advances in Social Science, Education and Humanities Research
Publication Date
13 February 2020
ISBN
10.2991/assehr.k.200205.025
ISSN
2352-5398
DOI
10.2991/assehr.k.200205.025How to use a DOI?
Copyright
© 2020, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Shen Li
AU  - Changle Zhang
AU  - Ke Zhang
AU  - Jumin Song
PY  - 2020
DA  - 2020/02/13
TI  - The Role of Cystatin C and Albumin in the Differential Diagnosis of Primary Chronic Glomerulonephritis and Hypertension-Induced Renal Injury
BT  - Proceedings of the Third International Conference on Social Science, Public Health and Education (SSPHE 2019)
PB  - Atlantis Press
SP  - 112
EP  - 115
SN  - 2352-5398
UR  - https://doi.org/10.2991/assehr.k.200205.025
DO  - 10.2991/assehr.k.200205.025
ID  - Li2020
ER  -