Relationship Between Catalase Enzyme Activity and Malondialdehyde (MDA) Levels in Incomplete Abortion and Imminent Abortion

DOI

10.2991/ahsr.k.211026.034How to use a DOI?

Keywords

Catalase enzyme activity, MDA levels, incomplete abortion, abortion imminent

Abstract

Abortion is one of the obstetric complications that are often found in pregnant women. The cause of abortion is not known with certainty, but it is suspected that one of the causes is an imbalance of pro-oxidants and antioxidants that occurs during placentation. Catalase is an enzyme that functions to catalyze hydrogen peroxide (H2O2) preventing lipid peroxidation in cell membranes. Malondialdehyde (MDA) is a product of lipid peroxidation. This review plans to decide the connection between catalase protein movement and malondialdehyde (MDA) levels in the incidence of incomplete and imminent abortion. The research was conducted at the Government General Hospital dr. M. Djamil, Hospital dr. Reksodiwiryo, and the Biochemistry Laboratory of Andalas University, Padang, with a cross-sectional design. The sample amounted to 42 people, consisting of three groups, namely incomplete abortion, imminent abortion and normal pregnant women 20 weeks as a control group, which were taken using consetic utuve sampling technique. Blood was gathered from the review subjects by intravenous means and estimated with a spectrophotomete. Based on the Pearson test, there was a huge negative connection between’s catalase protein movement and malondialdehyde (MDA) levels in the incidence of incomplete abortion (p=<0.05), and there was no significant correlation between catalase enzyme activity and malondialdehyde (MDA) levels in the incidence of abortion. imminent (p=>0.05). This study concludes that there is a significant negative correlation between catalase protein movement and malondialdehyde (MDA) levels, where low catalase protein movement can increase malondialdehyde (MDA) levels in the incidence of incomplete abortion.

Copyright

© 2021, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Melia Pebrina
AU  - Fenny Fernando
PY  - 2021
DA  - 2021/10/28
TI  - Relationship Between Catalase Enzyme Activity and Malondialdehyde (MDA) Levels in Incomplete Abortion and Imminent Abortion
BT  - Proceedings of the 2nd Syedza Saintika International Conference on Nursing, Midwifery, Medical Laboratory Technology, Public Health, and Health Information Management (SeSICNiMPH 2021)
PB  - Atlantis Press
SP  - 181
EP  - 187
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.211026.034
DO  - 10.2991/ahsr.k.211026.034
ID  - Pebrina2021
ER  -