Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)

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Management of Atypia of Undetermined Significant Thyroid Nodule

Authors
Ika Dewi Mayangsari*, Ferucha Moulanda
Division of Oncology, Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia
*Corresponding author. Email: idmayang@yahoo.com
Corresponding Author
Ika Dewi Mayangsari
Available Online 21 February 2022.
DOI
10.2991/ahsr.k.220206.068How to use a DOI?
Keywords
AUS; hemithyroidectomy; management; thyroid nodule
Abstract

Thyroid nodules are one of frequent clinical problem with prevalence of 5% palpable nodules. Results of atypia of undetermined significance (AUS) can be found with risk of 5-15% malignancy rates. Management of AUS is still challenging and complex including observation until surgical approach. We present two cases of nodule thyroid. The 1st case of 44-year-old female with nodule of left thyroid lobe for 1 year. Ultrasonography (USG) examination showed TIRADS 4 at left lobe yet the Fine needle aspiration (FNA) resulted as AUS. The 2nd case was 44-year-old male with nodule at left thyroid lobe for 3 years. USG showed TIRADS 5 of left lobe and TIRADS 4 of right lobe meanwhile FNA resulted as AUS. Left hemithyroidectomy was performed for the 1st patient and histopathology examinations showed as struma adenomatous with focus of thyroid papillary carcinoma with follicular variant. Completion thyroidectomy then performed 2 months after the first procedure. Observation was chosen for the 2nd case. Patient has been asymptomatic with close thyroid function and USG follow up. Hemithyroidectomy was performed 6 months afterwards since the mass getting bigger, and histopathology showed papillary carcinoma thus proceed with total thyroidectomy. Management of AUS is still debatable. It can present as heterogeneous lesions with different sub classifications according to cytomorphologic and molecular findings. Considerations of clinical risk stratification, USG findings and FNAB should be combined altogether for the best management and treatment outcome.

Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

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Volume Title
Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)
Series
Advances in Health Sciences Research
Publication Date
21 February 2022
ISBN
978-94-6239-540-4
ISSN
2468-5739
DOI
10.2991/ahsr.k.220206.068How to use a DOI?
Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

Cite this article

risenwbib
TY  - CONF
AU  - Ika Dewi Mayangsari
AU  - Ferucha Moulanda
PY  - 2022
DA  - 2022/02/21
TI  - Management of Atypia of Undetermined Significant Thyroid Nodule
BT  - Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)
PB  - Atlantis Press
SP  - 365
EP  - 369
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.220206.068
DO  - 10.2991/ahsr.k.220206.068
ID  - Mayangsari2022
ER  -