Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)

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Laboratory Profiles of Nasopharyngeal Carcinoma Patients

Authors
Nur Akbar Aroeman*, Ifiq Budiyan Nazar, Yussy Afriani Dewi
Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Padjadjaran/ Hasan Sadikin Hospital, Bandung, Indonesia
*Corresponding author. Email: aroeman_ent@yahoo.com
Corresponding Author
Nur Akbar Aroeman
Available Online 21 February 2022.
DOI
10.2991/ahsr.k.220206.072How to use a DOI?
Keywords
Nasopharyngeal Carcinoma; Laboratory Profiles; Prognosis; Predictors
Abstract

Nasopharyngeal Carcinoma (NPC) is one of the most common head and neck malignant neoplasms worldwide. Laboratory profile is rarely evaluated in Indonesia as a prognostic consideration. The aim of this research is to describe the laboratory profile of NPC patients. This is descriptive research using a total sampling method from 2016-to 2020. The general characteristics and laboratory profiles are collected from Nasopharyngeal Cancer Registry. The data collected will be presented in tables as frequency and percentages. More than half of the participants were male (68.27%), aged more than 45 years old (65.38%). The majority of the subjects reported a KPS of more than 80 (84.94%). Most of the participants showed WHO type III (47.57%). Bone (42.22%) was the most common metastases site. Normal hemoglobin (57.14%), leukocyte (57.99%), thrombocyte (91.36%), ALP (81.82%), AST (89.66%), ALT (61.26%), direct bilirubin (76.00%), indirect bilirubin (63.30%), total bilirubin (86.60%) and urea (84.10%) levels were found in most of our subjects. Calcium <8.6 mg/dL (92.21%) and creatinine >1.5 mg/dL (69.2%) were observed in most cases. This study indicated a worse prognosis by anemia, leukocytosis, and a high De Ritis ratio. In comparison, a better prognosis is predicted by low ALP levels, high calcium, direct bilirubin, and total bilirubin. In addition, pretreatment laboratory profiles should be assessed to predict the prognosis of patients with NPC.

Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

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Volume Title
Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)
Series
Advances in Health Sciences Research
Publication Date
21 February 2022
ISBN
10.2991/ahsr.k.220206.072
ISSN
2468-5739
DOI
10.2991/ahsr.k.220206.072How to use a DOI?
Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

Cite this article

risenwbib
TY  - CONF
AU  - Nur Akbar Aroeman
AU  - Ifiq Budiyan Nazar
AU  - Yussy Afriani Dewi
PY  - 2022
DA  - 2022/02/21
TI  - Laboratory Profiles of Nasopharyngeal Carcinoma Patients
BT  - Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)
PB  - Atlantis Press
SP  - 390
EP  - 396
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.220206.072
DO  - 10.2991/ahsr.k.220206.072
ID  - Aroeman2022
ER  -