Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)

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Association of Metabolic Syndrome with Cardiovascular Mortality in The Elderly: A Meta-Analysis

Authors
Erieka Febriayana Rosiva, Muhammad Miftahul Hadi, Yusra Pintaningrum*
Faculty of Medicine, Mataram University, Department of Cardiology, Mataram, Indonesia
*Corresponding author. Email: yusra@unram.ac.id
Corresponding Author
Yusra Pintaningrum
Available Online 21 February 2022.
DOI
10.2991/ahsr.k.220206.075How to use a DOI?
Keywords
Metabolic syndrome; Cardiovascular disease; Mortality; Elderly
Abstract

Metabolic syndrome should be considered an important issue in elderly individuals, as aging is a major contributor to the prevalence of the constellation of cardiovascular and metabolic risk factors that constitute the syndrome. However, recent studies that have investigated metabolic syndrome as a predictor of mortality in elderly shown conflicting results. The search was conducted using the PubMed, Cochrane library published in the last 20 years (January 2001 to January 2021). The search keynwords were “Metabolic syndrome”, “cardiovascular disease”, “Mortality” and “Elderly”. Data statistical analysis using Review Manager 5.3 (RevMan Cochrane, London, UK). Based on 6 prospective cohort studies, metabolic syndrome was associated with a higher risk of cardiovascular mortality when compared to non-cardiovascular mortality in the elderly (RR = 0,68; 95% CI=0,64-0,72; P=<0,00001), there was considerable heterogeneity in all studies used (I2=98%; P=0,00001). Factor explaining heterogeneity between studies included sex, age, sample size, prevalence of metabolic syndrome, follow-up duration, and definition of syndrome metabolic. Cardiovascular mortality compared to those non-cardiovascular mortality, had a higher in elderly with metabolic syndrome. High blood glucose and hypertension were the main components of the cause of death from cardiovascular disease in the elderly. In addition, the combination of several symptoms of metabolic syndrome has a different risk of death and requires further research in the future.

Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

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Volume Title
Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)
Series
Advances in Health Sciences Research
Publication Date
21 February 2022
ISBN
10.2991/ahsr.k.220206.075
ISSN
2468-5739
DOI
10.2991/ahsr.k.220206.075How to use a DOI?
Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

Cite this article

risenwbib
TY  - CONF
AU  - Erieka Febriayana Rosiva
AU  - Muhammad Miftahul Hadi
AU  - Yusra Pintaningrum
PY  - 2022
DA  - 2022/02/21
TI  - Association of Metabolic Syndrome with Cardiovascular Mortality in The Elderly: A Meta-Analysis
BT  - Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)
PB  - Atlantis Press
SP  - 407
EP  - 411
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.220206.075
DO  - 10.2991/ahsr.k.220206.075
ID  - Rosiva2022
ER  -