Studies on preparation of matrine solid dispersion sustained-release tablets

DOI

10.2991/msmee-17.2017.40How to use a DOI?

Keywords

matrine solid dispersion; sustained-release tablets; release rate

Abstract

Objective: Matrine was made into solid dispersion sustained-release tablets. Methods: Ingredients are screened by single factor test and orthogonal ,forming ingredient of sustained-release tablets was determined by appearance,formability, dissolution and d hardness of tablets. Results: The result showed that the optimum formulation was composed of HPMC 12g ,lactose 9.5,3%PVP 8ml,magnesium stearate 0.5g. Conclusion: Matrine solid dispersion sustained-release tablets meets the requirement of meets the requirements of suspension preparation with pharmacopoeia with stable quality.

Copyright

© 2017, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Zao-hui Li
AU  - Jiao Wang
PY  - 2017/05
DA  - 2017/05
TI  - Studies on preparation of matrine solid dispersion sustained-release tablets
BT  - Proceedings of the 2017 2nd International Conference on Materials Science, Machinery and Energy Engineering (MSMEE 2017)
PB  - Atlantis Press
SP  - 190
EP  - 198
SN  - 2352-5401
UR  - https://doi.org/10.2991/msmee-17.2017.40
DO  - 10.2991/msmee-17.2017.40
ID  - Li2017/05
ER  -