Possibility Forecasting of Progressive Neurological and Psychopathological Disorders in Chronic Mercury Intoxication

DOI

10.2991/itsmssm-16.2016.98How to use a DOI?

Keywords

Occupational chronic mercury toxicity, progression of the disease, psychiatric disorders

Abstract

Objectives: Of the research was to identify the most informative criteria of progression of chronic mercury intoxication and the possibility of its prediction using neuropsychological and neurophysiological methods. Material and Methods: For research were chosen 3 groups of patients with different degrees of severity of mercury intoxication. It is conducting a study of the emotional sphere, using the technique MMPI and the level of depression according to V. Zung, neuropsychological testing, EEG with the definition of auditory, visual, cognitive evoked potentials, somatosensory evoked potentials were assessed. Informative criteria were calculated using discriminant analysis. Results and Conclusions: The main markers of pathological changes in the early stages of the disease in an internship working in contact with mercury for more than 10 years, are: exceeding the normative values of 2nd and 8th scales MMPI from 70 points and more, exceeding the level of depression V. Zung from 54 points or more, reduction of attention concentration below 279 points, increase in the indicator of long-term, visual memory, finger gnosis and impressive speech from 0.5 points and above, and an increase in latency peak N11 somatosensory evoked potentials of 12 ms or higher, the increase in P2 visual evoked potentials from 260.0 ms and above, and decrease in the index of alpha rhythm on the EEG below 32%. With the combination of all four of these indicators of the likelihood of mercury poisoning was 91.3%. To predict the development of psycho-neurological symptoms, patients in contact with the mercury, it is necessary to conduct an annual comprehensive examination, including neuropsychological and neurophysiological methods.

Copyright

© 2016, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Elena Katamanova
AU  - Oxana Shevchenko
AU  - Viktor Rukavishnikov
AU  - Salim Shayakhmetov
AU  - Oleg Lakhman
PY  - 2016/05
DA  - 2016/05
TI  - Possibility Forecasting of Progressive Neurological and Psychopathological Disorders in Chronic Mercury Intoxication
BT  - Proceedings of the 2016 Conference on Information Technologies in Science, Management, Social Sphere and Medicine
PB  - Atlantis Press
SP  - 505
EP  - 510
SN  - 2352-538X
UR  - https://doi.org/10.2991/itsmssm-16.2016.98
DO  - 10.2991/itsmssm-16.2016.98
ID  - Katamanova2016/05
ER  -