Review of the computational models for the signaling pathway

DOI

10.2991/itoec-16.2016.21How to use a DOI?

Keywords

signaling pathway; computational models; systems biology

Abstract

In the past few years, systems biology methods have been widely used to explore the mechanism of cancer. Various signaling pathways play the important role in cancer. And a large number of computational methods are used to model the signaling pathway. Here, we reviewed many existing mechanisms and modeling techniques, which are used to model different signaling pathways. Then we introduced the systematic workflow of a system biology approach and some fundamental analysis methods. Finally we discuss some known challenges in the process of modeling signaling pathways and what we should handle in our future work.

Copyright

© 2016, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Meijing Kong
AU  - Chao Wang
AU  - Le Zhang
PY  - 2016/05
DA  - 2016/05
TI  - Review of the computational models for the signaling pathway
BT  - Proceedings of the 2nd Information Technology and Mechatronics Engineering Conference (ITOEC 2016)
PB  - Atlantis Press
SP  - 104
EP  - 110
SN  - 2352-5401
UR  - https://doi.org/10.2991/itoec-16.2016.21
DO  - 10.2991/itoec-16.2016.21
ID  - Kong2016/05
ER  -