Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)

Study and Modeling the Influence of a Solvent on Extraction of Eugenol from Laurus Nobilis L. Leaves

Authors
Valentina Radyukova, Nikolay Boyko, Elena Zhilyakova, Zoja Tsvetkova, Diana Martceva, Anastasia Malyutina, Valentina Kasakova, Daria Fadeeva, Ghadeer Balloul
Corresponding Author
Valentina Radyukova
Available Online November 2019.
DOI
10.2991/isils-19.2019.62How to use a DOI?
Keywords
Laurus nobilis L. leaves, solvents, HPLC analysis, dielectric constant, eugenol.
Abstract

this paper presents the results of a study and modeling of the influence of the solvent’s dielectric constant on the extraction of eugenol from the Laurus nobilis L leaves. The aim of this work is to study the effect of the solvent on the extraction of eugenol from the leaves of Laurus nobilis L., to propose a theoretical model for describing the results. Shredded plant material of Laurus nobilis L. leaves 0.1-0.5 mm. Aqueous solutions of ethanol (23, 39, 55, 73, 80, 96±1% v/v). The extracts were obtained by a ratio of plant materials - extractant 1:5 (w/v), insisting for 24 hours at a temperature of 24±1°C. Analysis of the extracts was carried out using reverse phase high performance liquid chromatography and a standard sample of eugenol. The dependence of the concentration of eugenol in alcohol-water extracts on the concentration of ethanol in solution was studied. It was found that the maximum concentration of eugenol is observed in solutions with ethanol concentrations of 85±15 % vol. This range of ethanol concentrations corresponds to a dielectric constant of the solvent of 33.5±3.5 units. The regression equation of the dependence of the concentration of eugenol in the extract on the dielectric constant of alcohol-water solutions is obtained. It was found that the dielectric constant of the solvent has the most significant effect on the process of isolating the phytocomponent from plant materials. A mathematical model is theoretically grounded and tested to describe the dependence of the concentration of eugenol on the dielectric constant of water-ethanol solutions. The optimal range of solvent dielectric constant was found to achieve the maximum concentration of eugenol in the extract.

Copyright
© 2019, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)
Series
Advances in Biological Sciences Research
Publication Date
November 2019
ISBN
10.2991/isils-19.2019.62
ISSN
2468-5747
DOI
10.2991/isils-19.2019.62How to use a DOI?
Copyright
© 2019, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Valentina Radyukova
AU  - Nikolay Boyko
AU  - Elena Zhilyakova
AU  - Zoja Tsvetkova
AU  - Diana Martceva
AU  - Anastasia Malyutina
AU  - Valentina Kasakova
AU  - Daria Fadeeva
AU  - Ghadeer Balloul
PY  - 2019/11
DA  - 2019/11
TI  - Study and Modeling the Influence of a Solvent on Extraction of Eugenol from Laurus Nobilis L. Leaves
BT  - Proceedings of the 1st International Symposium Innovations in Life Sciences (ISILS 2019)
PB  - Atlantis Press
SP  - 356
EP  - 359
SN  - 2468-5747
UR  - https://doi.org/10.2991/isils-19.2019.62
DO  - 10.2991/isils-19.2019.62
ID  - Radyukova2019/11
ER  -