Characterization and Antibacterial Activity Test of Hand Sanitizer Gel Ethanol Extract Ficus lyrata Warb Against Escherichia coli Bacteria
- DOI
- 10.2991/isessah-19.2019.17How to use a DOI?
- Keywords
- Antibacterial, Escherichia coli, Ficus lyrata Warb, Hand sanitizer, Total Plate Count (TPC)
- Abstract
Diarrhea is a disease caused by the lack of maintenance of hand hygiene. One of the pathogenic bacteria that causes diarrheal disease is Escherichia coli. The way to maintain the hygiene of the hands of pathogenic bacterial attacks is to use antiseptic. The type of antiseptic that can be applied is Hand sanitizer. Ficus lyrata Warb is an annual plant known as the shade and protective plant. Ficus lyrata fruit has the content of phenolic compounds, flavonoids and tannins, which have the potential to be an anti-bacterial. The purpose of this research is to find out the antibacterial activity of Ficus lyrata fruit extract in hand sanitizer to reduce the number of bacteria on the hands. This type of research is experimental laboratories. Ficus lyrata Warb Fruit Extraction uses a maceration method with 70% ethanol solvent. The Ficus lyrata Warb fruit extract is made from a variety of concentrations of 100%, 75%, 50% and 25% tested antibacterial activity against Escherichia coli bacteria using the disk diffusion method with Amoxicillin as positive control and DMSO 50% as negative control. Effectiveness of the hand sanitizer with Ficus lyrata fruit extract in the hand, is tested using the Total Plate Count (TPC) method. Research Data is analyzed descriptively. The test results of antibacterial activity at a concentration of 75% resulted in the average diameter of the largest barrier of 1.75 mm but not greater than the positive control of 26, 25mm. The result of TPC test, Hand sanitizer Ficus lyrata Warb fruit extract is able to reduce the number of bacteria on the hands from 0.90 × 102 Cfu's/mL to 0.30 × 101 Cfu's/mL
- Copyright
- © 2019, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Dwi Wira AU - Selly Putri AU - Efri Mardawati AU - Hilma Kamila AU - Roostita Balia PY - 2019/12 DA - 2019/12 TI - Characterization and Antibacterial Activity Test of Hand Sanitizer Gel Ethanol Extract Ficus lyrata Warb Against Escherichia coli Bacteria BT - Proceedings of the Conference of the International Society for Economics and Social Sciences of Animal Health - South East Asia 2019 (ISESSAH-SEA 2019) PB - Atlantis Press SP - 75 EP - 78 SN - 2468-5739 UR - https://doi.org/10.2991/isessah-19.2019.17 DO - 10.2991/isessah-19.2019.17 ID - Wira2019/12 ER -