Proceedings of the 1st International Conference Postgraduate School Universitas Airlangga : "Implementation of Climate Change Agreement to Meet Sustainable Development Goals" (ICPSUAS 2017)

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EFEKTIVENESS TEST OF AKAR KUCING PLANT EXTRACT (Acalypha indica Linn) TO LOWER TOTAL CHOLESTEROL LEVELS IN RATS (Rattus novergicus) WHICH INDUCED HYPERCHOLESTEROLEMIA DIET

Authors
Retno Sri Wahyuni, Fitria Agung Nugrahaningtyas, Nove Hidayati, Rochmah Kurnijasanti
Corresponding Author
Retno Sri Wahyuni
Available Online August 2017.
DOI
10.2991/icpsuas-17.2018.79How to use a DOI?
Keywords
Acalypha indica Linn., total cholesterol, hypercholesterolemia
Abstract

This research aims to determine the effect of ethanol extract of Acalypha indica Linn. on levels of total cholesterol of rat that is induced pig oil. This was an experimental research. The sample used was 20 rats were divided into 5 groups (1 group is consist of 4 rats), namely: 1) positive control, 2) negative control, 3) extract dose of 200 mg/kgBB, 4) extract dose of 400 mg/kgBB, 5) extract dose of 800 mg/kgBB. Group 2 to 5 are given pig oil as hypercholesterolemia diet, given for 28 days, then given treatment appropiate with the group. The result show that: 1) the average of total cholesterol levels increased after administration pork oil from 160 mg/dL to 232 mg/dL, 2) at a dose of 200 mg/kgBB, 400 mg/kgBB and 800 mg/kgBB showed a decline in total cholesterol levels by 189 mg/dl, 128 mg/dl, and 177 mg/dl. The result of this research concluse that Acalypha indica Linn. extract at dose of 200 mg/kgBB, 400 mg/kgBB and 800 mg kgBB have an effect in lowering total cholesterol of rat had been induced pork oil.

Copyright
© 2018, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 1st International Conference Postgraduate School Universitas Airlangga : "Implementation of Climate Change Agreement to Meet Sustainable Development Goals" (ICPSUAS 2017)
Series
Advances in Social Science, Education and Humanities Research
Publication Date
August 2017
ISBN
978-94-6252-461-3
ISSN
2352-5398
DOI
10.2991/icpsuas-17.2018.79How to use a DOI?
Copyright
© 2018, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

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TY  - CONF
AU  - Retno Sri Wahyuni
AU  - Fitria Agung Nugrahaningtyas
AU  - Nove Hidayati
AU  - Rochmah Kurnijasanti
PY  - 2017/08
DA  - 2017/08
TI  - EFEKTIVENESS TEST OF AKAR KUCING PLANT EXTRACT (Acalypha indica Linn) TO LOWER TOTAL CHOLESTEROL LEVELS IN RATS (Rattus novergicus) WHICH INDUCED HYPERCHOLESTEROLEMIA DIET
BT  - Proceedings of the 1st International Conference Postgraduate School Universitas Airlangga : "Implementation of Climate Change Agreement to Meet Sustainable Development Goals" (ICPSUAS 2017)
PB  - Atlantis Press
SP  - 365
EP  - 367
SN  - 2352-5398
UR  - https://doi.org/10.2991/icpsuas-17.2018.79
DO  - 10.2991/icpsuas-17.2018.79
ID  - SriWahyuni2017/08
ER  -