Neurodegeneration and Huntington’s disease
- DOI
- 10.2991/assehr.k.220110.141How to use a DOI?
- Keywords
- Huntington’s disease; neurodegenerative disorder; treatment; chromosome; newborn cells
- Abstract
Neurodegeneration is related to many kinds of age-related neuron diseases. Taking Huntington’s disease(HD) as an example, it is a fatal hereditary neurodegenerative disorder caused by expanded CAG repeats in specific genes. There is no fundamental treatment for HD, and the mechanism of its occurrence and development is unclear. Currently, there are only drugs that improve individual symptoms, and lose effectiveness after a certain period of time due to resistance. In order to better understand the pathogenesis of this kind of disease and explore more feasible treatment methods, the author briefly reviews the research of basic pathology of this kind of disease, and selecting HD to discuss deeply for its possible treatment means. The result shows that the gene-related brain structural changes is closely related to the occurrence of disease, and it is a genetic disease. Since disease treatments and drugs must be screened and validated in animal models, it is very important to establish cell and animal models that can accurately simulate disease phenotypes and pathology to develop effective disease treatments.
- Copyright
- © 2022 The Authors. Published by Atlantis Press SARL.
- Open Access
- This is an open access article under the CC BY-NC license.
Cite this article
TY - CONF AU - Yintao Kang PY - 2022 DA - 2022/01/28 TI - Neurodegeneration and Huntington’s disease BT - Proceedings of the 2021 International Conference on Public Art and Human Development ( ICPAHD 2021) PB - Atlantis Press SP - 736 EP - 739 SN - 2352-5398 UR - https://doi.org/10.2991/assehr.k.220110.141 DO - 10.2991/assehr.k.220110.141 ID - Kang2022 ER -