Proceedings of the International Conference on Medical Science and Health (ICOMESH 2024)

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Relationship Between Increased Levels of Hepar Transaminase Enzymes and The Severity of Dengue Infection in Pediatric Patients

Authors
Oktadoni Saputra1, *
1Department of Pediatric, Faculty of Medicine, Lampung University, Bandar Lampung, Indonesia
*Corresponding author. Email: okta_ds@yahoo.com
Corresponding Author
Oktadoni Saputra
Available Online 19 December 2024.
DOI
10.2991/978-94-6463-604-8_4How to use a DOI?
Keywords
ALT; AST; Dengue; Pediatric
Abstract

Dengue is an infectious disease occurring worldwide. This infection is caused by the dengue virus transmitted by Aedes aegypti and Aedes albopictus mosquitoes. Dengue infection is recorded to reach as many as 400 million cases annually, with 100 million patients experiencing symptoms due to the infection, and 40,000 people dying from severe dengue. One of the warning signs of dengue infection is the enlargement of the liver (>2cm). This hepatomegaly condition indicates liver damage identified through physical examination by palpation of the liver. To assess liver damage causing a decrease in liver function, laboratory tests such as SGOT and SGPT are required. This study is an observational analytical research employing a cross-sectional approach. The study is prospective cohort. Bivariate analysis was conducted using Spearman's test. In the test of the relationship between the severity of dengue and the increase in SGOT, a p-value of 0.239 was obtained (p > 0.05). In the test of the relationship between the severity of dengue and the increase in SGPT, a p-value of 0.153 was obtained (p > 0.05). There is no correlation between the increase in hepatic transaminase enzymes and the severity of dengue infection in pediatric patients at Abdul Moeloek Hospital in Bandar Lampung in 2023.

Copyright
© 2024 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the International Conference on Medical Science and Health (ICOMESH 2024)
Series
Advances in Health Sciences Research
Publication Date
19 December 2024
ISBN
978-94-6463-604-8
ISSN
2468-5739
DOI
10.2991/978-94-6463-604-8_4How to use a DOI?
Copyright
© 2024 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Oktadoni Saputra
PY  - 2024
DA  - 2024/12/19
TI  - Relationship Between Increased Levels of Hepar Transaminase Enzymes and The Severity of Dengue Infection in Pediatric Patients
BT  - Proceedings of the International Conference on Medical Science and Health (ICOMESH 2024)
PB  - Atlantis Press
SP  - 38
EP  - 43
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-604-8_4
DO  - 10.2991/978-94-6463-604-8_4
ID  - Saputra2024
ER  -