Proceedings of the International Conference of Medical and Life Science (ICoMELISA 2021)

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Potential of Clinacanthus Nutans as an Alternative Therapeutic Agent for Diabetes Mellitus

Authors
Nurlaili Susanti1, *
1UIN Maulana Malik Ibrahim, Malang, Indonesia
*Corresponding author. Email: nurlaili.susanti@kedokteran.uin-malang.ac.id
Corresponding Author
Nurlaili Susanti
Available Online 26 June 2023.
DOI
10.2991/978-94-6463-208-8_6How to use a DOI?
Keywords
Medicinal plants; Clinacanthus nutans; antidiabetic; antioxidant
Abstract

Target various aspects of the pathway in DM. One of plant traditionally used in Southeast Asia for diabetes treatment is Clinacanthus nutans (CN). Several studies have proven the pharmacological activity of CN as an antidiabetic. This study aims to review the potential of CN as an antidiabetic and discuss its possible mechanism of action. We present a literature review of original article regarding the antidiabetic effect of CN using invitro and/or invivo models. The article were obtain through Google Scholar database from 2012–2020 using the keywords “Clinacanthus nutans”, “antidiabetic”, and “hypoglycemia”. A total of 39 article were obtained, 25 articles were excluded being not relevant and the remaining 14 articles were selected for the study. CN possess antidiabetic effect through inhibition α-glucosidase, increasing insulin secretion and improving insulin resistance. This effect related to its antioxidant activity. Clinacanthus nutans can be selected as a source of industrial product development for the treatment of DM according to its medicinal value. The mechanism of action is still unclear, so further research are needed.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the International Conference of Medical and Life Science (ICoMELISA 2021)
Series
Advances in Health Sciences Research
Publication Date
26 June 2023
ISBN
10.2991/978-94-6463-208-8_6
ISSN
2468-5739
DOI
10.2991/978-94-6463-208-8_6How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Nurlaili Susanti
PY  - 2023
DA  - 2023/06/26
TI  - Potential of Clinacanthus Nutans as an Alternative Therapeutic Agent for Diabetes Mellitus
BT  - Proceedings of the International Conference of Medical and Life Science (ICoMELISA 2021)
PB  - Atlantis Press
SP  - 27
EP  - 36
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-208-8_6
DO  - 10.2991/978-94-6463-208-8_6
ID  - Susanti2023
ER  -