Development of Medical Devices Based on Protein Marker for Animal and Human Diseases

DOI

10.2991/icoh-17.2018.2How to use a DOI?

Keywords

Medical devices, Immunochromatography technique, Protein marker

Abstract

The concept of medical devices based on immunochromatography, is a combination of chromatography technique (for separation of sample components based on differences of their movement through the sorbent) and the immunochemical reaction that has been implemented in various ways. In this review, we discuss the evolution of immunoblotting techniques during the last decades, and was followed by development of reverse/lateral flow immunochromatography technique, also its use in various fields of biomedical research, food technology and explore the future direction for continuous improvement. The aim of this review is to improve the understanding of reverse/lateral flow immunochromatography technology, enabling the production of better products to be made, and provide impetus for further advances in technology. Lateral flow immunochromatography were first launched commercially in 1984, as a simple urine-based pregnancy test for home use. In the early 1980's, two new rapid immunodiagnostic platforms were invented, namely the lateral-flow test and flow-through test (or vertical-flow test), both completing in the healthcare market. We highlight some successfully commercialized rapid test for both human and animal. In order to have a rapid test product that have a high sensitivity and specificity, the point to note is the antigen or antibody used for the detection marker. We have developed several rapid diagnostic tests by reverse flow immunochromatography assay for metabolic disorders and infectious diseases. To be able to produce a good rapid test, should be developed based on the patho-mechanism of the disease, so it is important to choose a protein marker that appears in the early stages of disease.

Copyright

© 2018, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Aulanni'am Aulanni'am
PY  - 2017/07
DA  - 2017/07
TI  - Development of Medical Devices Based on Protein Marker for Animal and Human Diseases
BT  - Proceedings of the 1st International Conference in One Health (ICOH 2017)
PB  - Atlantis Press
SP  - 5
EP  - 8
SN  - 2468-5739
UR  - https://doi.org/10.2991/icoh-17.2018.2
DO  - 10.2991/icoh-17.2018.2
ID  - Aulanni'am2017/07
ER  -