Analysis of Clinical Medication Rule of Trigonellae Semen Based on Data Mining

DOI

10.2991/icmesd-19.2019.76How to use a DOI?

Keywords

Trigonellae Semen, Data mining, Medication rule

Abstract

Objective: To further explore the clinical medication rule of Trigonellae Semen and analyze the potential compatibility relationship of traditional Chinese medicine (TCM) . Method: The clinical application literature of Trigonellae Semen in CNKI and Wanfang database is screened. Excel 2013 is used to establish the database of the selected prescriptions, and Apriori algorithm of SPSS Modeler 14.1 is used to analyze the association rules, mining the application rules of Trigonellae Semen in clinical compatibility. Result: Among the 71 prescriptions selected, 186 Chinese medicines are used, 730 times in total. Except Trigonellae Semen, the top five high-frequency Chinese medicines are Angelica, Astragalus, Epimedium, Atractylodes Macrocephala and Prepared Rhubarb. The most commonly used Chinese medicines are deficiency-Nourishing Drugs, blood-activating and Stasis-eliminating, and heat-clearing drug. Sweet, pungent and bitter in flavor,warm in nature, the three meridians of liver, kidney and spleen are the most frequently used. Fourteen highly correlated combinations of traditional Chinese medicines are obtained. Fifteen and thirteen combinations of TCM are obtained from the analysis of medication for gynecological and renal diseases. Conclusion: Trigonellae Semen has obvious compatibility relationship with TCM in the use of gynecological and kidney diseases. We should attach importance to the compatibility of Trigonellae Semen with Cyperi Rhizoma, Semen Litchi , Corydalis Rhizoma, Angelica, Prepared Rhubarb and Rhizoma Smilacis Glabrae in order to produce better clinical efficacy.

Copyright

© 2019, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Download article (PDF)

TY  - CONF
AU  - Jing-Yi Qiao
AU  - Jing Chen
AU  - Jing-Jing Shi
AU  - Ming-San Miao
PY  - 2019/07
DA  - 2019/07
TI  - Analysis of Clinical Medication Rule of Trigonellae Semen Based on Data Mining
BT  - Proceedings of the 5th Annual International Conference on Management, Economics and Social Development (ICMESD 2019)
PB  - Atlantis Press
SP  - 484
EP  - 488
SN  - 2352-5428
UR  - https://doi.org/10.2991/icmesd-19.2019.76
DO  - 10.2991/icmesd-19.2019.76
ID  - Qiao2019/07
ER  -