DNA Methylation on Bloodstain as a Forensic Age Estimation Method
- DOI
- 10.2991/aebmr.k.200513.006How to use a DOI?
- Keywords
- age, bloodstain, DNA methylation, estimation, forensic
- Abstract
Forensic identification is an effort to help law enforcement in determining a person’s identity. Personal identity is often a problem in criminal cases, civil cases, death without identity, and mass disasters. Age estimation is very important in forensic identification. DNA methylation is a potential epigenetic modification for age estimation because DNA in aging process resembles developments that are regulated in processes that are tightly controlled by specific epigenetic modifications. In most cases of violent crime, bloodstains can be found at the crime scene. Bloodstain may come from victims, perpetrators of crime, or even from both. Bloodstain can be used to help reveal the fact scientifically Correlation between DNA methylation from bloodstain and a person’s age is unknown. The study aims to determine the correlation of DNA methylation from bloodstain and a person’s age. The study was conducted at the Institute of Tropical Disease of Universitas Airlangga from July to October 2019. The research method used was analytic observational which was conducted on 10 samples with details of 5 male and 5 female samples. The results of the study, correlation of DNA methylation with age in male subjects correlation coefficient was 0.888 with a significance value of 0.04 and in female subjects correlation coefficient was 0.834 with a significance value of 0.079. The conclusion, there is a significant correlation between percent methylation with age in male subjects, whereas in female subjects there was no significant correlation.
- Copyright
- © 2020, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Ahmad Yudianto AU - Masniari Novita AU - Muhammad Afiful Jauhani AU - Deka Bagus Binarsa PY - 2020 DA - 2020/05/20 TI - DNA Methylation on Bloodstain as a Forensic Age Estimation Method BT - Proceedings of the International Conference on Law, Economics and Health (ICLEH 2020) PB - Atlantis Press SP - 31 EP - 33 SN - 2352-5428 UR - https://doi.org/10.2991/aebmr.k.200513.006 DO - 10.2991/aebmr.k.200513.006 ID - Yudianto2020 ER -