The Effect of Chitosan on the Formation of Odontoblast-Like Cells in Reversible Pulpitis (in Vivo Study on Sprague Dawley Rats)

DOI

10.2991/978-94-6463-184-5_5How to use a DOI?

Keywords

Reversible pulpitis; Chitosan red snapper scales; Direct pulp cap; Odontoblast-like cell

Abstract

Reversible pulpitis is inflammation of the pulp that can change back to the normal pulp. The medicament is critical to the success of direct pulp capping treatment, as evidenced by the formation of odontoblast-like cells. Calcium hydroxide has begun to be abandoned because of its deficiency. This study aims to determine the effect of chitosan-coated red snapper fish scales as a medicament for direct pulp capping on the formation of odontoblast-like cells. This study examined the effect of chitosan on the formation of odontoblast-like cells in vivo. The samples used were from 4 groups: healthy rats, reversible pulpitis rats, reversible pulpitis rats treated with calcium hydroxide, and reversible pulpitis rats treated with chitosan. Observation of odontoblast-like cells was carried out using an Optilab Olympus CX23 microscope with a magnification of 1000 times and was calculated using image raster software. The results showed the formation of odontoblast-like cells with an average of in group 1 0.166, group 2 0.066, group 3 0.600, and group 4 0.633. Then the Kruskal Wallis test was carried out, and the results obtained were p = 0.006 (p < 0.05), meaning a significant difference. The results of the Mann-Whitney test showed that there were significant and insignificant differences. Based on this study, it can be concluded that chitosan red snapper fish scales used as a direct pulp capping material influence the formation of odontoblast-like cells in reversible pulpitis.

Copyright

© 2023 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Amara Syifa Tifani
AU  - Noor Hafida Widyastuti
AU  - Nur Ariska Nugrahani
AU  - Cahyani Cahyani
PY  - 2023
DA  - 2023/05/30
TI  - The Effect of Chitosan on the Formation of Odontoblast-Like Cells in Reversible Pulpitis (in Vivo Study on Sprague Dawley Rats)
BT  - Proceedings of the International Conference on Health and Well-Being (ICHWB 2022)
PB  - Atlantis Press
SP  - 33
EP  - 39
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-184-5_5
DO  - 10.2991/978-94-6463-184-5_5
ID  - Tifani2023
ER  -