Prospects for the Prevention of Premature Aging With Plant Antioxidants

DOI

10.2991/ahsr.k.201001.056How to use a DOI?

Keywords

aging, nutrition, resveratrol, Amur grapes, preventive efficacy

Abstract

Insenescence has intrigued and concerned scientists from the very beginning of civilization. It is a process that can be broadly described as changes that occur during the life cycle of an organism that gradually increases the likelihood of their death. The changes that lead to a gradual increase in the likelihood of mortality span all aspects of biology, from molecular mechanisms to physiological systems of the whole body. Moreover, there is no doubt that aging is externally modulated by lifestyle and diet, while the rate of aging appears to be determined by a wide variety of genetic mutations. In this regard, the prevention of aging is especially relevant, using biologically active substances obtained from wild-growing raw materials with an acceptable safety profile. Resveratrol obtained from Amur grapes can be safely attributed to such substances. The scientific article presents the results of a study of resveratrol as a means of preventing the aging process in animals. The article analyzed the dynamics of changes in lipid peroxidation and peroxide resistance of erythrocytes under conditions of acute stress. As a result of the conducted studies, it was found that the effect of stress contributes to an increase in the degree of hemolysis of erythrocytes, as well as an increase in the content of liver lipid peroxidation products. However, the introduction of resveratrol into the diet of the studied animals contributed to a decrease in lipid peroxidation in the liver of animals and an increase in the resistance of erythrocytes to the action of peroxide compounds, which indicates a slowdown in the aging rate.

Copyright

© 2020, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Download article (PDF)

TY  - CONF
AU  - A. Praskova Yulia
AU  - A. Frolova Nina
AU  - F. Kiseleva Tatiana
AU  - S. Matyushchenko Victoria
AU  - Yu. Reznichenko Irina
PY  - 2020
DA  - 2020/10/03
TI  - Prospects for the Prevention of Premature Aging With Plant Antioxidants
BT  - Proceedings of the International Conference “Health and wellbeing in modern society” (ICHW 2020)
PB  - Atlantis Press
SP  - 277
EP  - 281
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.201001.056
DO  - 10.2991/ahsr.k.201001.056
ID  - PraskovaYulia2020
ER  -