Proceedings of selected papers of International Conference on Health, Science, and Environment (ICHSE 2023)

<Previous Article In Volume
Next Article In Volume>

Combination of Jamblang Leaf Extract (Syzygium cumini) and Vitamin C Increased Albumin and Decreased Bilirubin Serum Level on Lead Acetate Induced Rats

Authors
Rauza Sukma Rita1, *, Endrinaldi1, Tofrizal2
1Department of Biochemistry, Faculty of Medicine, Universitas Andalas, Padang, 25163, Indonesia
2Department of Anatomical Pathology, Faculty of Medicine, Universitas Andalas, Padang, 25163, Indonesia
*Corresponding author. Email: rauzasukmarita@med.unand.ac.id
Corresponding Author
Rauza Sukma Rita
Available Online 30 May 2024.
DOI
10.2991/978-94-6463-431-0_7How to use a DOI?
Keywords
Syzigium cumini; vitamin C; albumin; bilirubin; lead acetate; rats
Abstract

Oxidative stress from lead acetate can impair organ function. Antioxidants, which can be obtained from plants like Syzigium cumini, are necessary to counter oxidative stress. This study aimed to analyze the effect of the combination of jamblang leaf extract and vitamin C on serum albumin and bilirubin levels in lead-acetate-induced rats. This study was conducted on 35 rats divided into five groups: a negative control group (only given food and drink), a positive control group induced by lead acetate 40 mg/kg body weight, and treatment groups induced by lead acetate with three combination doses of jamblang leaf extract and vitamin C (35 mg/kg BW and 15 mg/kg BW; 75 mg/kg BW and 35 mg/kg BW; and 150 mg/kg BW and 75 mg/kg BW). Serum albumin and bilirubin levels were read with a spectrophotometer. The results showed that combination therapy of jamblang leaf extract with vitamin C increased albumin levels and reduced serum bilirubin levels after lead acetate administration significantly (p<0.05). This study concludes that the combination therapy of jamblang leaf extract and vitamin C affects serum albumin and bilirubin levels.

Copyright
© 2024 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Download article (PDF)

<Previous Article In Volume
Next Article In Volume>
Volume Title
Proceedings of selected papers of International Conference on Health, Science, and Environment (ICHSE 2023)
Series
Advances in Biological Sciences Research
Publication Date
30 May 2024
ISBN
10.2991/978-94-6463-431-0_7
ISSN
2468-5747
DOI
10.2991/978-94-6463-431-0_7How to use a DOI?
Copyright
© 2024 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Rauza Sukma Rita
AU  - Endrinaldi
AU  - Tofrizal
PY  - 2024
DA  - 2024/05/30
TI  - Combination of Jamblang Leaf Extract (Syzygium cumini) and Vitamin C Increased Albumin and Decreased Bilirubin Serum Level on Lead Acetate Induced Rats
BT  - Proceedings of selected papers of International Conference on Health, Science, and Environment (ICHSE 2023)
PB  - Atlantis Press
SP  - 55
EP  - 62
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-431-0_7
DO  - 10.2991/978-94-6463-431-0_7
ID  - Rita2024
ER  -