Proceedings of the 3rd International Conference on Environmentally Sustainable Animal Industry 2022 (ICESAI 2022)

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Antibacterial Activity of Sargassum sp. Extract Encapsulated into Chitosan-Tripolyphosphate Nanoparticles

Authors
Faizal Andri1, 2, Nanung Danar Dono3, Heru Sasongko3, Zuprizal Zuprizal3, *
1Faculty of Animal Science, Universitas Gadjah Mada, 55281, Yogyakarta, Indonesia
2Faculty of Animal Science, Universitas Brawijaya, 65145, Malang, Indonesia
3Faculty of Animal Science, Universitas Gadjah Mada, 55281, Yogyakarta, Indonesia
*Corresponding author. Email: zuprizal@ugm.ac.id
Corresponding Author
Zuprizal Zuprizal
Available Online 8 March 2023.
DOI
10.2991/978-94-6463-116-6_35How to use a DOI?
Keywords
antibiotics; nanoparticles; Sargassum sp.; Escherichia coli; Salmonella sp
Abstract

This study aimed to evaluate the antibacterial activity of Sargassum sp. Extract encapsulated into chitosan-tripolyphosphate nanoparticles. Sargassum sp. Extract was prepared by maceration using ethanol 96% (1:10) for 24 h. Four nanoparticles formula were synthesized with the chitosan:Sargassum sp. Extract:tripolyphosphate ratios of 4:0:2 (F0), 4:1:2 (F1), 4:2:2 (F2), and 4:4:2 (F3). The nanoparticles along with aquadest, zinc bacitracin (10 mg/mL), and free Sargassum sp. Extract (100 mg/mL) were then tested for antibacterial activity against Escherichia coli and Salmonella sp. Using agar well diffusion method. Results showed that the incorporation of Sargassum sp. Extract into chitosan-tripolyphosphate nanoparticles provided a significant effect on antibacterial activity (P < 0.05). F2 has higher Escherichia coli and Salmonella sp. Inhibition than that of F0 and F1 (P < 0.05) but did not differ when compared with F3. F2 has equivalent Escherichia coli inhibition as compared to zinc bacitracin and free Sargassum sp. Extract. Moreover, F2 has higher antibacterial activity against Salmonella sp. (P < 0.05) than that of zinc bacitracin and free Sargassum sp. Extract. It could be concluded that Sargassum sp. Extract encapsulated into chitosan-tripolyphosphate nanoparticles is a promising candidate as an antibiotic alternative in poultry nutrition. Nano-F2 provided the optimum antibacterial activity against E. coli and Salmonella sp. Among the tested nanoparticles formula.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 3rd International Conference on Environmentally Sustainable Animal Industry 2022 (ICESAI 2022)
Series
Advances in Biological Sciences Research
Publication Date
8 March 2023
ISBN
978-94-6463-116-6
ISSN
2468-5747
DOI
10.2991/978-94-6463-116-6_35How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Faizal Andri
AU  - Nanung Danar Dono
AU  - Heru Sasongko
AU  - Zuprizal Zuprizal
PY  - 2023
DA  - 2023/03/08
TI  - Antibacterial Activity of Sargassum sp. Extract Encapsulated into Chitosan-Tripolyphosphate Nanoparticles
BT  - Proceedings of the 3rd International Conference on Environmentally Sustainable Animal Industry 2022 (ICESAI 2022)
PB  - Atlantis Press
SP  - 280
EP  - 286
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-116-6_35
DO  - 10.2991/978-94-6463-116-6_35
ID  - Andri2023
ER  -