Proceedings of the 2nd International Conference on Contemporary Science and Clinical Pharmacy 2021 (ICCSCP 2021)

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Formulation and Antibacterial Activity of Natural Disinfectant Combination of Psidium guajava and Piper betle Leaf Infusion Against Staphylococcus aureus

Authors
Nori Wirahmi1, *, Camelia Dwi Putri Masrijal1, Zul Amri2, Ikhsan1, Muhammad Ichsan Triyansyah1
1Diploma Program of Pharmacy, Faculty of Mathematics and Natural Science, Universitas Bengkulu, Bengkulu, Indonesia
2National Agency of Drug and Food Control, Bengkulu, Indonesia
*Corresponding author.Email: nwirahmi.@unib.ac.id
Corresponding Author
Nori Wirahmi
Available Online 17 November 2021.
DOI
10.2991/ahsr.k.211105.013How to use a DOI?
Keywords
Natural disinfectant; Psidium guajava; Piper betle; leaf infusion; antibacterial activity; Staphylococcus aureus
Abstract

Spraying disinfectant all over the body in the disinfection room is being used to prevent the spread of the SARS- CoV-2 as the cause of the Covid-19 disease. Due to chemical disinfectants have high toxicity to the body, a relatively safe natural disinfectant is needed. The purposes of this study were to obtain a natural disinfectant solution formula combination of guava leaf infusion (Psidium guajava L.) and betle leaf infusion (Piper betle L.) and to determine the antibacterial activity of these formulas. In this research, a combination formula of guava leaf and betle leaf infusion with three formulas were formulated, contains 20% guava leaf infusion and 25% betle leaf with ratio of 1: 3, 1: 1, and 3:1 respectively, namely F2, F3 and F4. F0 was chemical disinfectant as positive control and F1 as negative control. Antibacterial activity test against Staphylococcus aureus conducted on a petri dish using disc diffusion method. The highest inhibition zone was formed by F4 with average diameter of 10.2 mm, categorized as strong level of antibacterial activity against Staphylococcus aureus. The results confirmed that natural disinfectant solution formula combination of guava leaf infusion and betle leaf infusion had potential agents as natural disinfectant.

Copyright
© 2021 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

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Volume Title
Proceedings of the 2nd International Conference on Contemporary Science and Clinical Pharmacy 2021 (ICCSCP 2021)
Series
Advances in Health Sciences Research
Publication Date
17 November 2021
ISBN
10.2991/ahsr.k.211105.013
ISSN
2468-5739
DOI
10.2991/ahsr.k.211105.013How to use a DOI?
Copyright
© 2021 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

Cite this article

risenwbib
TY  - CONF
AU  - Nori Wirahmi
AU  - Camelia Dwi Putri Masrijal
AU  - Zul Amri
AU  - Ikhsan
AU  - Muhammad Ichsan Triyansyah
PY  - 2021
DA  - 2021/11/17
TI  - Formulation and Antibacterial Activity of Natural Disinfectant Combination of Psidium guajava and Piper betle Leaf Infusion Against Staphylococcus aureus
BT  - Proceedings of the 2nd International Conference on Contemporary Science and Clinical Pharmacy 2021 (ICCSCP 2021)
PB  - Atlantis Press
SP  - 91
EP  - 97
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.211105.013
DO  - 10.2991/ahsr.k.211105.013
ID  - Wirahmi2021
ER  -