CdSe Quantum dots Molecular Beacon Hybridization with Target Telomerase DNA Specificity
- 10.2991/icaemt-15.2015.175How to use a DOI?
- Cdse Quantum Dots, Molecular Beacon, Telomerase DNA, One-Pot Approach
Quantum Dots are powerful imaging and tracking tools for a wide range of biomedical applications, especially in preparing molecular beacons, but its use is limited by the sensitivity of the electrostatic binding between streptavidin and QDs. In this investigation, we used EDC as a crosslinker and NHS as a stabilizer to activate the carboxyl groups of carboxyl-modified CdSe QDs for direct reaction with primary amines of amino-modified single-stranded DNA. The results suggest that CdSe QDs can be applied for preparing the molecular beacon hybridized with specific telomerase DNA.
- © 2015, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Linyan Shen AU - Ming Ying AU - Pengfei Deng PY - 2015/08 DA - 2015/08 TI - CdSe Quantum dots Molecular Beacon Hybridization with Target Telomerase DNA Specificity BT - Proceedings of the 2015 International Conference on Advanced Engineering Materials and Technology PB - Atlantis Press SP - 925 EP - 928 SN - 2352-5401 UR - https://doi.org/10.2991/icaemt-15.2015.175 DO - 10.2991/icaemt-15.2015.175 ID - Shen2015/08 ER -