Proceedings of the 3rd International Conference on Material, Mechanical and Manufacturing Engineering

Antihyperglycemic Activity of Banana (Musa nana Lour.) Peel and Its Active Ingredients in Alloxan-Induced Diabetic Mice

Authors
Hongmei Wu, Feng Xu, Junjie Hao, Ye Yang, Xiangpei Wang
Corresponding Author
Hongmei Wu
Available Online August 2015.
DOI
10.2991/ic3me-15.2015.44How to use a DOI?
Keywords
Banana peel, Musa nana Lour., lupenone, antihyperglycemic, -sitosterol
Abstract

Previous studies have found that banana flowers, leaves, pseudostems, roots, infructescence stalks, and peels (M. paradisiacal (Linn.)) have antihyperglycemic effect. The banana peel (Musa nana Lour.) might have the antihyperglycemic activity, its antihyperglycemic activity and active ingredients remain to be elucidated. In this paper, fresh banana peel was sequential extraction using solvents with decreasing polarity. Then, the ethyl acetate and petroleum ether extracts (EBP and PBP) were chosen to evaluate the antihyperglycemic activity in alloxan-induced diabetic mice. And the antihyperglycemic activity guided fractionation of compounds. The EBP displayed potent antihyperglycemic activity. lupenone and -sitosterol were separated from EBP. Animal experiments results indicated that lupenone could effective reduce blood glucose of diabetic mice. The banana peel and its ingredient lupenone showed promising antihyperglycemic activity. The banana peel could be utilized as a natural source of antihyperglycemic food, health care or drug and lupenone has potential to develop as an antihyperglycemic drug.

Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 3rd International Conference on Material, Mechanical and Manufacturing Engineering
Series
Advances in Engineering Research
Publication Date
August 2015
ISBN
978-94-6252-100-1
ISSN
2352-5401
DOI
10.2991/ic3me-15.2015.44How to use a DOI?
Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Hongmei Wu
AU  - Feng Xu
AU  - Junjie Hao
AU  - Ye Yang
AU  - Xiangpei Wang
PY  - 2015/08
DA  - 2015/08
TI  - Antihyperglycemic Activity of Banana (Musa nana Lour.) Peel and Its Active Ingredients in Alloxan-Induced Diabetic Mice
BT  - Proceedings of the 3rd International Conference on Material, Mechanical and Manufacturing Engineering
PB  - Atlantis Press
SP  - 231
EP  - 238
SN  - 2352-5401
UR  - https://doi.org/10.2991/ic3me-15.2015.44
DO  - 10.2991/ic3me-15.2015.44
ID  - Wu2015/08
ER  -