Antihyperglycemic Activity of Banana (Musa nana Lour.) Peel and Its Active Ingredients in Alloxan-Induced Diabetic Mice
- DOI
- 10.2991/ic3me-15.2015.44How to use a DOI?
- Keywords
- Banana peel, Musa nana Lour., lupenone, antihyperglycemic, -sitosterol
- Abstract
Previous studies have found that banana flowers, leaves, pseudostems, roots, infructescence stalks, and peels (M. paradisiacal (Linn.)) have antihyperglycemic effect. The banana peel (Musa nana Lour.) might have the antihyperglycemic activity, its antihyperglycemic activity and active ingredients remain to be elucidated. In this paper, fresh banana peel was sequential extraction using solvents with decreasing polarity. Then, the ethyl acetate and petroleum ether extracts (EBP and PBP) were chosen to evaluate the antihyperglycemic activity in alloxan-induced diabetic mice. And the antihyperglycemic activity guided fractionation of compounds. The EBP displayed potent antihyperglycemic activity. lupenone and -sitosterol were separated from EBP. Animal experiments results indicated that lupenone could effective reduce blood glucose of diabetic mice. The banana peel and its ingredient lupenone showed promising antihyperglycemic activity. The banana peel could be utilized as a natural source of antihyperglycemic food, health care or drug and lupenone has potential to develop as an antihyperglycemic drug.
- Copyright
- © 2015, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Hongmei Wu AU - Feng Xu AU - Junjie Hao AU - Ye Yang AU - Xiangpei Wang PY - 2015/08 DA - 2015/08 TI - Antihyperglycemic Activity of Banana (Musa nana Lour.) Peel and Its Active Ingredients in Alloxan-Induced Diabetic Mice BT - Proceedings of the 3rd International Conference on Material, Mechanical and Manufacturing Engineering PB - Atlantis Press SP - 231 EP - 238 SN - 2352-5401 UR - https://doi.org/10.2991/ic3me-15.2015.44 DO - 10.2991/ic3me-15.2015.44 ID - Wu2015/08 ER -