Proceedings of the 3rd International Conference on Material, Mechanical and Manufacturing Engineering

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Improved synthesis of miriplatin, an antitumor drug

Authors
Qingkun Wang, Shaoping Pu
Corresponding Author
Qingkun Wang
Available Online August 2015.
DOI
10.2991/ic3me-15.2015.41How to use a DOI?
Keywords
antitumor drug; miriplatin; improved synthesis
Abstract

Miriplatin, a novel lipophilic platinum complex has been developed to treat hepatocellular carcinoma. An improvd synthetic route was designed and used to prepare the target compound. Pt(C6H14N2)I2 was reacted with CH3(CH2)12COOAg in water subsequently product was separated from AgI by dissolved in ethanol. The structure of the target compound was identified by elemental analysis, ESI-MS, FT-IR, 1H-NMR, the structure was consistent with the target compound.

Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 3rd International Conference on Material, Mechanical and Manufacturing Engineering
Series
Advances in Engineering Research
Publication Date
August 2015
ISBN
978-94-6252-100-1
ISSN
2352-5401
DOI
10.2991/ic3me-15.2015.41How to use a DOI?
Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Qingkun Wang
AU  - Shaoping Pu
PY  - 2015/08
DA  - 2015/08
TI  - Improved synthesis of miriplatin, an antitumor drug
BT  - Proceedings of the 3rd International Conference on Material, Mechanical and Manufacturing Engineering
PB  - Atlantis Press
SP  - 212
EP  - 215
SN  - 2352-5401
UR  - https://doi.org/10.2991/ic3me-15.2015.41
DO  - 10.2991/ic3me-15.2015.41
ID  - Wang2015/08
ER  -