Antioxidant Activity of Methanolic Extract of Ficus elastica L. Leaves

DOI

10.2991/ahsr.k.200523.015How to use a DOI?

Keywords

Ficus elastica L. leaf, antioxidant, DPPH, IC50

Abstract

Objectives: Natural antioxidants have an important role in the prevention of many diseases and promotion of health. Many natural sources of antioxidants derived from plants that ware spread throughout the plant. Phenolic compounds are potent antioxidants. The Ficus elastica L. (F. elastica) leaf is one of the sources that contain phenolic compounds. This study aims to determine the antioxidant activity of methanol extracts of F. elastica leaves which extracted in an acidic environment. Simplisia F. elastica leaves macerated in methanol solvent with the addition of HCI 2 N to pH 2. The antioxidant activity test was carried out by the DPPH method. Phytochemical screening results showed flavonoids, tannins, polyphenols, saponins, quinones, monoterpenoids, and sesquiterpenoids. The qualitative tested of antioxidant activity by TLC method showed the presence of antioxidant activity which was marked by the formation of faded yellow spots against the background of the purple TLC plate after being sprayed with a DPPH of 0.2%. These results strengthened by the results of quantitative antioxidant activity testing which shows that the methanol extract of Ficus elastica L. leaves has a very high antioxidant potential with an IC50 value of 7,6906±0,3 μg/ml with an IC50 value of standard compound (ascorbic acid) of 5,6109±0,5 μg/ml.

Copyright

© 2020, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Vera Nurviana
AU  - Lilis Tuslinah
AU  - Susanti
PY  - 2020
DA  - 2020/06/08
TI  - Antioxidant Activity of Methanolic Extract of Ficus elastica L. Leaves
BT  - The proceedings of the 2nd Bakti Tunas Husada-Health Science International Conference (BTH-HSIC 2019)
PB  - Atlantis Press
SP  - 53
EP  - 56
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.200523.015
DO  - 10.2991/ahsr.k.200523.015
ID  - Nurviana2020
ER  -