Clinical Pharmacoepidemiology Study of Antihypertensive and Antidiabetes Mellitus Drug in DM-Hypertensive Outpatient in a Private Hospital

DOI

10.2991/adics-phs-19.2019.10How to use a DOI?

Keywords

combination-therapy antihypertension, diabetes mellitus, hypertension, normal-blood pressure

Abstract

Diabetes mellitus and hypertension are degene-rative diseases that require long-term treatment. This study aims to describe the anti DM and antihypertensive drug therapy, clinical output, and the relationship of combination therapy with the clinical output of DM patients with hypertension in private hospitals in Yogyakarta. This study included an observational analytic study with a retrospective cohort design. The sample in this study were 100 DM patients with hypertension with ICD E.11.9 and I.10. The data obtained were analyzed by univariate and bivariate. The bivariate analysis used was chi-square to determine the relationship between combination therapy and clinical outcomes in the form of normal blood sugar levels and blood pressure. The results showed that the most widely used antidiabetic and antihypertensive use was metformin 15.2%, metformin-insulin as part mix 18.4%, amlodipine 14%, and candesartan-amlodipine 12.6%. Most DM patients with hypertension have a blood sugar level and normal blood pressure. The chi-square test results showed that there was a correlation between combination antiDM or antihypertensive therapy with a normal status of blood sugar levels or blood pressure (p <0.05). The conclusion of combination antiDM treatment is not related to the increasing achievement of average blood sugar level status in DM patients with hypertension. Combined antihypertensive treatment increases the chances of DM patients with hyper-tension achieving normal blood pressure status

Copyright

© 2019, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Download article (PDF)

TY  - CONF
AU  - Akrom Akrom
AU  - Muna Marzuqoh
PY  - 2019/11
DA  - 2019/11
TI  - Clinical Pharmacoepidemiology Study of Antihypertensive and Antidiabetes Mellitus Drug in DM-Hypertensive Outpatient in a Private Hospital
BT  - Proceedings of the 2019 Ahmad Dahlan International Conference Series on Pharmacy and Health Science (ADICS-PHS 2019)
PB  - Atlantis Press
SP  - 91
EP  - 99
SN  - 2468-5739
UR  - https://doi.org/10.2991/adics-phs-19.2019.10
DO  - 10.2991/adics-phs-19.2019.10
ID  - Akrom2019/11
ER  -