Clinical Hematology International

In Press, Corrected Proof, Available Online: 24 September 2019

Managing Endocrine Disorders in Adults After Hematopoietic Stem Cell Transplantation

Authors
Juliana Matthews1, *, Dwight Eplin2, Bipin Savani3, Barbara Gisella Carranza Leon1, Leslee Matheny1
1 Division of Diabetes, Endocrinology, and Metabolism, Vanderbilt University Medical Center, Nashville, TN
2 Division of Stem Cell Transplant, Veterans Affairs Medical Center, Nashville, TN
3 Division of Hematology and Oncology, Vanderbilt University Medical Center & Veterans Affairs Medical Center, Nashville, TN
*Corresponding author. Email: Juliana.j.matthews@vumc.org
Corresponding Author
Juliana Matthews
Received 14 June 2019, Accepted 26 August 2019, Available Online 24 September 2019.
DOI
https://doi.org/10.2991/chi.d.190917.001How to use a DOI?
Keywords
Stem cell transplant, Endocrine complications, Post-transplant diabetes, Transplant complications, Transplant survivorship
Abstract

Hematopoietic stem cell transplantation (HSCT) has become a potentially curative therapy for an increasing number of malignant and non-malignant conditions. As survival rates continue to improve, the focus of patient care has shifted from managing not only immediate but also long-term complications. Endocrine disorders are among the most prevalent late effects following HSCT. Detecting and treating such conditions offer new challenges, as well as opportunities to reduce preventable morbidity and mortality associated with HSCT. Our objective is to summarize recent literature and describe practical approaches to screening for and managing endocrine-related late effects. We focus on dyslipidemia, diabetes, thyroid disorders, osteoporosis, and hypogonadism. Mechanisms, monitoring, and management recommendations for each disorder are outlined. Growing data on these disorders in the post-transplant setting highlight the need for future study and evidence-based guidelines.

Copyright
© 2019 International Academy for Clinical Hematology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal
Clinical Hematology International
Publication Date
2019/09
ISSN (Online)
2590-0048
DOI
https://doi.org/10.2991/chi.d.190917.001How to use a DOI?
Copyright
© 2019 International Academy for Clinical Hematology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Juliana Matthews
AU  - Dwight Eplin
AU  - Bipin Savani
AU  - Barbara Gisella Carranza Leon
AU  - Leslee Matheny
PY  - 2019
DA  - 2019/09
TI  - Managing Endocrine Disorders in Adults After Hematopoietic Stem Cell Transplantation
JO  - Clinical Hematology International
SN  - 2590-0048
UR  - https://doi.org/10.2991/chi.d.190917.001
DO  - https://doi.org/10.2991/chi.d.190917.001
ID  - Matthews2019
ER  -