Artery Research

Volume 7, Issue 3-4, September 2013, Pages 156 - 156

P6.09 MULTIPLE REFLECTIONS, NOT A SINGLE DISTAL AORTIC REFLECTION DETERMINE PRESSURE WAVE SHAPE

Authors
N. Westerhof1, B.E. Westerhof2
1VU University Medical Center, Amsterdam, Netherlands
2Edwards Lifesciences BMEYE, Amsterdam, Netherlands
Available Online 11 November 2013.
DOI
10.1016/j.artres.2013.10.190How to use a DOI?
Abstract

Arterial pressure and flow waves travel and are reflected. Waveform analysis and wave separation gave insight into these phenomena and parameters thus obtained are indicators of cardiovascular events. However, the interpretation of forward and reflected waves is still not generally agreed upon. We used an anatomically accurate (data from Hickson, 2010) model of the entire systemic arterial tree and also set all aortic diameters equal at mean aortic diameter (“uniform aorta”), leaving other arteries unchanged, and calculated forward and backward waves in the standard way (Murgo, 1981). In the anatomically accurate model, timing of the feet of backward and forward waves is location independent, as also recently reported by Tyberg, 2013. In the uniform aorta the delay between forward and backward waves is smallest in the distal aorta and largest in the ascending aorta. In both models pressure amplification over the aorta is ∼1.35. Changes in microcirculatory resistance have little effect on wave shapes. We conclude that multiple local reflections in the aorta importantly contribute to pressure (and flow) wave shape. Thus pressure wave shapes depend on arterial geometry: aortic diameters and side branches. Distal aortic (bifurcation) and peripheral reflections are not the major contributors to overall reflection and wave shape. We suggest that studies of aortic dimensions and effect of side branches are needed to better understand aortic pressure wave shapes and wave travel.

Open Access
This is an open access article distributed under the CC BY-NC license.

Download article (PDF)
View full text (HTML)

Journal
Artery Research
Volume-Issue
7 - 3-4
Pages
156 - 156
Publication Date
2013/11/11
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2013.10.190How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - N. Westerhof
AU  - B.E. Westerhof
PY  - 2013
DA  - 2013/11/11
TI  - P6.09 MULTIPLE REFLECTIONS, NOT A SINGLE DISTAL AORTIC REFLECTION DETERMINE PRESSURE WAVE SHAPE
JO  - Artery Research
SP  - 156
EP  - 156
VL  - 7
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2013.10.190
DO  - 10.1016/j.artres.2013.10.190
ID  - Westerhof2013
ER  -