Artery Research

Volume 7, Issue 3-4, September 2013, Pages 150 - 150

P5.25 DIURNAL VARIATION OF CARDIO-ANKLE VASCULAR INDEX IN INDIVIDUALS WITH AND WITHOUT HEART DISEASE

Authors
Yanlei Li, Cordes Mareike, Hanssen Henner, Schmidt-Trucksäss Arno
Division Sports Medicine, Institute of Exercise and Health Sciences, University of Basel, Basel, Switzerland
Available Online 11 November 2013.
DOI
10.1016/j.artres.2013.10.173How to use a DOI?
Abstract

Background: Clinical studies revealed age and pathological-related arterial stiffening. Arterial stiffening is associated with a higher risk of cardiovascular disease. Cardio-ankle vascular index (CAVI), which reflects both central elastic and peripheral muscular arterial stiffness, has been applied as a simple noninvasive method to evaluate the risk for cardiovascular events. However, whether it is necessary to standardize the time of the day when performing this measurement is unknown. We aim to examine the effect of daytime on CAVI in individuals with and without heart disease.

Methods: We investigated the daytime variation of CAVI using Vasera VS-1500N (Fukuda Denshi; Japan) in 23 healthy young individuals (28.3±4.7yr, HY), 22 healthy elderly individuals (61.1±9.0 yr, HE) and 25 patients with heart disease (63.9±11.5yr, HD).

Results: The effect of time on CAVI was shown to be significant in both univariate and multivariate analysis. Age was found as a significant determinant of CAVI (p<0.001). After adjustment for age, sex and MAP, CAVI was shown to be 4% (09:00 versus 13:00, p=0.022) and 5% higher (09:00 versus 17:00, p=0.002) in the morning than the following time points. Furthermore, the patterns of variation over the day showed no significant differences among groups in CAVI.

Conclusion: CAVI showed a significantly higher value in the morning, which provides further support to standardize the time for measurements of arterial stiffness using CAVI in routine clinical practice and longitudinal studies.

Open Access
This is an open access article distributed under the CC BY-NC license.

Journal
Artery Research
Volume-Issue
7 - 3-4
Pages
150 - 150
Publication Date
2013/11/11
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2013.10.173How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Yanlei Li
AU  - Cordes Mareike
AU  - Hanssen Henner
AU  - Schmidt-Trucksäss Arno
PY  - 2013
DA  - 2013/11/11
TI  - P5.25 DIURNAL VARIATION OF CARDIO-ANKLE VASCULAR INDEX IN INDIVIDUALS WITH AND WITHOUT HEART DISEASE
JO  - Artery Research
SP  - 150
EP  - 150
VL  - 7
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2013.10.173
DO  - 10.1016/j.artres.2013.10.173
ID  - Li2013
ER  -