P2.24 A COMPARISON OF AORTIC PULSE WAVE VELOCITY MEASURED BY COMPLIOR AND SPHYGMOCOR IN PATIENTS WITH COPD AND HEALTHY VOLUNTEERS

DOI

10.1016/j.artres.2013.10.085How to use a DOI?

Abstract

Objectives: A number of non-invasive devices have been used to measure arterial stiffness in COPD. The aim of this study was to compare the Complior device with the gold standard SphygmoCor Vx device, in patients with COPD and healthy volunteers.

Methods: Aortic PWV was measured during a single visit in 18 (10 male) patients with COPD and 39 (18 male) healthy volunteers. Using Complior with the intersecting tangent alogarithm, PWV was derived using a direct carotid-femoral artery measurement x0.8 in 20 subjects, and a subtractive distance (carotid artery to sternal notch and sternal notch to femoral artery) in 37 subjects. All SphymoCor measurements were calculated using the subtractive distance.

Results: Patients and volunteers were similar in gender, mean age 67years and BMI 26.5kg/m². Using Complior there was no difference in PWV between the direct or subtractive path length in patients or volunteers. Using pooled data, there was no difference in PWV between Complior and SphygmoCor in COPD, and moderate consistency with an intraclass correlation coefficient (ICC) of 0.64. Pooled data for volunteers showed a mean difference in PWV of 1.0 (1.2)m/s (p<0.05) but consistency was high ICC 0.92. Bland-Altman plots showed no systematic bias with only one outlier in each group, but greater variability in COPD (Figure 1a&b).

Conclusion: There was no difference and moderate consistency in PWV measured by Complior and SphygmCor in COPD. However in healthy volunteers PWV differed between devices but showed high consistency. Although Complior and SphygmoCor were consistent they should not be used interchangeably.

Figure 1

Bland-Altman plot comparing PWV by Complior and SphygmoCor in a) Patients with COPD b) Volunteers.

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TY  - JOUR
AU  - K.E. Munnery
AU  - N.S. Gale
AU  - I.C. Munnery
AU  - C. Tyler
AU  - J.R. Cockcroft
PY  - 2013
DA  - 2013/11/11
TI  - P2.24 A COMPARISON OF AORTIC PULSE WAVE VELOCITY MEASURED BY COMPLIOR AND SPHYGMOCOR IN PATIENTS WITH COPD AND HEALTHY VOLUNTEERS
JO  - Artery Research
SP  - 125
EP  - 126
VL  - 7
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2013.10.085
DO  - 10.1016/j.artres.2013.10.085
ID  - Munnery2013
ER  -