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Volume 25, Issue Supplement 1, December 2019, Pages S185 - S185

P148 The Administration of Green Tea Extract Improves Hemodynamic Parameters, Arterial Stiffness and Renal Function in Patients with Diabetic Nephropathy

Authors
Marycruz Barocio*, Fernando Grover, Mayra Jiménez, Mariana Larios, Patricia Quezada, Jhonatan Trujillo, Ernesto Cardona, David Cardona, Carlos Ramos
University of Guadalajara, Guadalajara, Mexico
*Corresponding author. Email: marycruz_bp91@hotmail.com
Corresponding Author
Marycruz Barocio
Available Online 17 February 2020.
DOI
10.2991/artres.k.191224.168How to use a DOI?
Abstract

Purpose/Background/Objectives: Type 2 Diabetes Mellitus (T2DM) is a disease characterized by macro and microvascular complications, particularly, coronary heart disease, cerebrovascular disease and nephropathy [1–4]. The green tea extract has shown an anti-inflammatory effect (2), so this nutraceutical could be an alternative adjuvant in the treatment of the patient with diabetic nephropathy (DN) [5–7]. To evaluate the effect of the administration of green tea extract on hemodynamic, arterial stiffness, metabolic and renal function parameters in patients with DN.

Design and Methods: It was a randomized, double-blind study performed in 28 patients with DN, 14 assigned to placebo and 14 green tea extract, 400 mg every 12 hours for 12 weeks. Hemodynamic and arterial stiffness parameters were determined with HEM-9000AI, VP1000 Omron and metabolic parameters and renal function with Erba XL-100 equipment.

Results: The group under green tea extract treatment had significant decrease in the systolic blood pressure (mmHg) compared to those under placebo (−4.3 ± 12.7 vs 5.4 ± 12.2), central pressure (mmHg) (−6.0 ± 13.4 vs 9.1 ± 14.4), pulse pressure (mmHg) (−3.5 ± 6.6 vs 3.3 ± 6.4), triglycerides (mg/dl) (−16.4 ± 46.7 vs 30.3 ± 35.9), creatinine (−1.3 ± 0.2 vs 0.1 ± 0.1) and GFR (ml/min/1.73 m2) [8] (6.2 ± 5.9 vs −7.7 ± 10.9).

Conclusion: The administration of green tea extract improves hemodynamic parameters, metabolic parameters and renal function in patients with DM2 and chronic kidney disease.

Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
25 - Supplement 1
Pages
S185 - S185
Publication Date
2020/02/17
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.191224.168How to use a DOI?
Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - JOUR
AU  - Marycruz Barocio
AU  - Fernando Grover
AU  - Mayra Jiménez
AU  - Mariana Larios
AU  - Patricia Quezada
AU  - Jhonatan Trujillo
AU  - Ernesto Cardona
AU  - David Cardona
AU  - Carlos Ramos
PY  - 2020
DA  - 2020/02/17
TI  - P148 The Administration of Green Tea Extract Improves Hemodynamic Parameters, Arterial Stiffness and Renal Function in Patients with Diabetic Nephropathy
JO  - Artery Research
SP  - S185
EP  - S185
VL  - 25
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191224.168
DO  - 10.2991/artres.k.191224.168
ID  - Barocio2020
ER  -