Artery Research

Volume 25, Issue Supplement 1, December 2019, Pages S187 - S187

P150 Study of Heamodynamic and Macrocirculation Indices Between Uncontrolled Naïve Hypertensives and Well Controlled Diabetic Patients

Authors
Areti Triantafyllou, Nick Koletsos, Konstantina Dipla, Ioanna Zografou, Xristos Avgerinos, Stauros Papadopoulos, Alexandros-Savvas Zafeiridis, Stella Kritikou, Eugenia Gkaliagkousi, Andreas Zafeiridis, Stella Douma
Aristotle University of Thessaloniki, Greece
Available Online 17 February 2020.
DOI
10.2991/artres.k.191224.170How to use a DOI?
Abstract

Introduction: Both Type II Diabetes mellitus (DM) and hypertension have been associated with an increased risk for cardiovascular disease and linked to impairments in micro- and macrocirculation. However, previous studies examining micro- and macrocirculation in DM mainly include patients with comorbid hypertension. Therefore, the aim of the study was to compare hemodynamic and vascular indices in DM and non-DM patients, independently of their hypertension status.

Materials and Methods: Fifty-seven DM patients and 79 non-DM participants were enrolled. Participants underwent physical examination, ambulatory BP monitoring and estimation of pulse wave velocity (PWV) and intima-media thickness (IMT). Resting hemodynamic parameters were assessed by impedance cardiography. Participants also performed a 3-min-submaximal isometric handgrip (30% MVC) with continuous beat-by-beat BP/HR assessment (Finapress). The double product (DP = systolic blood pressure* heart rate) during HG was calculated, as an index of myocardial stress.

Results: No differences were observed in age, BMI, and resting BP among groups. Patients with DM had significantly higher PWV and IMT (p < 0.01) but lower velocity (VI) and acceleration index (ACI) compared to non-DM individuals (p < 0.05). Hypertensives had significantly higher myocardial stress during exercise compared to normotensives, independently of the presence of diabetes.

Conclusion: Despite similar blood pressure levels in DM and non-DM groups, the DM patients had higher PWV and IMT than non-DM participants. There were no differences between patients with isolated adequately controlled DM or isolated hypertension in macrocirculation indices, suggesting a possible equal impact of the above diseases on the macrovascular network.

Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Download article (PDF)
View full text (HTML)

Journal
Artery Research
Volume-Issue
25 - Supplement 1
Pages
S187 - S187
Publication Date
2020/02/17
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.191224.170How to use a DOI?
Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Areti Triantafyllou
AU  - Nick Koletsos
AU  - Konstantina Dipla
AU  - Ioanna Zografou
AU  - Xristos Avgerinos
AU  - Stauros Papadopoulos
AU  - Alexandros-Savvas Zafeiridis
AU  - Stella Kritikou
AU  - Eugenia Gkaliagkousi
AU  - Andreas Zafeiridis
AU  - Stella Douma
PY  - 2020
DA  - 2020/02/17
TI  - P150 Study of Heamodynamic and Macrocirculation Indices Between Uncontrolled Naïve Hypertensives and Well Controlled Diabetic Patients
JO  - Artery Research
SP  - S187
EP  - S187
VL  - 25
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191224.170
DO  - 10.2991/artres.k.191224.170
ID  - Triantafyllou2020
ER  -