Artery Research

Volume 25, Issue Supplement 1, December 2019, Pages S140 - S140

P101 Arterial Stiffness vs Sarcopenia in Portuguese Elderly Population

Authors
Valentina Vassilenko1, 4, 5, Andreia Serrano1, 4, 5, Beatriz Ramalho1, Paulo Bonifácio1, 4, 5, Ana C. Coelho2, Fernando Pimentel-Santos3
1Laboratory of Instrumentation, Biomedical Engineering and Radiation Physics (LIBPHYS), NOVA School of Science and Technology - NOVA University Lisbon, 2829-516 Caparica, Portugal
2Santa Casa da Misericórdia de Almada, Portugal
3Centre for Chronic Diseases, Nova Medical School (CEDOC|FCM- UNL), Lisbon, Portugal
4NMT, S.A., Parque Tecnológico de Cantanhede, Núcleo 04, Portugal
5Iberian Network on Central Hemodynamic and Arterial Structure, Lisbon, Portugal
Available Online 17 February 2020.
DOI
10.2991/artres.k.191224.127How to use a DOI?
Abstract

Aging often results in the appearance of sarcopenia, which is characterized by loss of muscle mass and strength. The incidence of sarcopenia in the elderly is a quite common and leads to weakness and disability, as well as a lower quality of life, also assuming a high social and economic impact. One previous study has shown an independent negative association between arterial stiffness and skeletal muscle mass decline [1], which suggest its relationship with sarcopenia. This work aims to evaluate the relation between sarcopenia and the arterial stiffness, in Portuguese elderly population A cohort of 38 elderly volunteers between 67 and 95 years, with and without Sarcopenia, were selected from nursing homes and day centers of Portuguese charity institution - Santa Casa da Misericórdia de Almada. All volunteers have the same living condition, meals and lifestyle routine, excepting the medications. The diagnosis and degree (severe or moderate) of sarcopenia were performed according to the European consensus on definition and diagnosis of sarcopenia [2] at the same day with arterial stiffnesses measurements assessed by carotid-femoral Pulse Wave Velocity (cfPWV). Our data show a positive correlation for cfPWV with the sarcopenia severity degree, which represents an increasing in arterial stiffness and might be explained by the fact that the loss of muscle mass is often associated with chronic inflammation [3]. Despite of the small cohort size, the male gender held a bigger mean value of cfPWV, with significant p-value (0.014), in comparison to the female gender, which estimates a higher CV risk for the male elders of the region of Almada and Greater Lisbon compared to the female gender. Further investigations would be desirable in order to obtain larger samples and ascertain the estimates for the respective groups.

Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Journal
Artery Research
Volume-Issue
25 - Supplement 1
Pages
S140 - S140
Publication Date
2020/02/17
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.191224.127How to use a DOI?
Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Valentina Vassilenko
AU  - Andreia Serrano
AU  - Beatriz Ramalho
AU  - Paulo Bonifácio
AU  - Ana C. Coelho
AU  - Fernando Pimentel-Santos
PY  - 2020
DA  - 2020/02/17
TI  - P101 Arterial Stiffness vs Sarcopenia in Portuguese Elderly Population
JO  - Artery Research
SP  - S140
EP  - S140
VL  - 25
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191224.127
DO  - 10.2991/artres.k.191224.127
ID  - Vassilenko2020
ER  -