Artery Research

Volume 25, Issue Supplement 1, December 2019, Pages S75 - S75

P34 24-Hour Ambulatory Brachial Versus Aortic Systolic Blood Pressure: Relationship with Left Ventricular Mass Significantly Differs. Pooled Results from the International 24 Hour Aortic Blood Pressure Consortium (i24ABC)

Authors
Siegfried Wassertheurer1, *, Athanase Protogerou2, James Sharman3, Enrique Rodilla Sala4, Piotr Jankowski5, Maria Lorenza Muiesan6, Cristina Giannattasio7, Bernhard Hametner8, Jose Maria Pascual4, Robert Zweiker9, Antonio Argyris2, Anna Paini6, Ian Wilkinson10, Danuta Czarnecka5, Massimo Salvetti6, Alessandro Maloberti7, Carmel McEniery10, Yan Li11, Janos Nemcsik12, Giacomo Pucci13, Cornelia Ablasser9, Jacques Blacher14, Alexandre Valleé14, Alejandro de la Sierra15, Yi Zhang16, Hongwei Ji16, Barry McDonnell17, Marco Mota18, Annelise Paiva18, Andrea Brandao18, Thomas Weber19
1AIT Austrian Institute of Technology, Vienna, Austria
2Cardiovascular Prevention and Research Unit, Department of Pathophysiology, Medical School, Laiko Hospital, National and Kapodistrian University of Athens, Greece
3Menzies Institute for Medical Research, College of Health and Medicine, University of Tasmania, Australia
4Department of Medicina Interna, Hospital de Sagunto, Universidad Cardenal Herrera-CEU, CEU Universities, Valencia, Spain
5Department of Cardiology, Interventional Electrocardiology and Hypertension, Jagiellonian University, Medical College, Krakow, Poland
6Department of Clinical and Experimental Sciences, University of Brescia, Italy
7Cardiology IV, 'A. De Gasperis' Department, ASTT Ospedale Niguarda Ca' Granda, School of Medicine and Surgery Department, Milano-Bicocca University, Milan, Italy
8Center for Health and Bioresources, Department of Health and Environment, Austrian Institute of Technology, Vienna, Austria
9Cardiology Department, Medical University Graz, Austria
10Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, UK
11Ruijin Hospital, Shanghai Jiaotong University School of Medicine
12Semmelweis University Budapest, Hungary
13Unit of Internal Medicine, Terni University Hospital, Department of Medicine, University of Perugia, Italy
14Diagnosis and Therapeutic Center, Hotel Dieu; AP-HP; University Paris Descartes, France
15Hospital Mutua Terrassa, University of Barcelona, Spain
16Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, China
17Cardiff Metropolitan University, UK
18Centro Universitário Cesmac/Hospital do Coração de Alagoas, Maceió Brazil
19Klinikum Wels-Grieskirchen, Kardiologie, Wels, Austria
*Corresponding author. Email: siegfried.wassertheurer@ait.ac.at
Corresponding Author
Siegfried Wassertheurer
Available Online 15 February 2020.
DOI
10.2991/artres.k.191224.066How to use a DOI?
Abstract

Background: There is evidence of a closer relation between 24 hour aortic systolic blood pressure (aSBP) and left ventricular mass (LVM) compared with 24 hour brachial SBP. However, sample sizes are relatively small and there is some inconsistency in findings. We sought to address this by pooling data from 16 centers in Asia, Europe and Latin America to determine the relationship between LVM and brachial office, as well as brachial and aortic 24 hour ambulatory SBP.

Methods: In all centers, brachial and aortic SBP was measured with the same validated oscillometric device, using a transfer function for aortic pressure, and mean/diastolic pressure calibration. LVM was determined by echocardiography.

Results: We studied 2092 participants (972 women) with a mean age of 52 years. Mean brachial office BP was 137/84 mmHg, and mean 24 hour bSBP and aSBP was 126 [118;134] and 131 [120;137] mm Hg, respectively. Mean LVM indexed to body surface area was 88.4 g/m2, and 27.2% of participants had left ventricular hypertrophy (LVH). The correlation coefficients between LVM and brachial office SBP, 24 hour bSBP, and 24 hour aSBP were 0.24, 0.35, and 0.43, respectively (p < 0.001 for differences). The areas under the curve for prediction of LVH were 0.62, 0.67, and 0.70 for brachial office SBP, 24 hour bSBP, and 24 hour aSBP, respectively (p < 0.001 for differences).

Conclusion: In this pooled analysis of international data, we demonstrate that aortic ambulatory SBP, measured with an oscillometric cuff, shows a significantly closer association with hypertensive cardiac organ damage (left ventricular mass and hypertrophy) than brachial office/brachial ambulatory systolic blood pressure.

Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Journal
Artery Research
Volume-Issue
25 - Supplement 1
Pages
S75 - S75
Publication Date
2020/02/15
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.191224.066How to use a DOI?
Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Siegfried Wassertheurer
AU  - Athanase Protogerou
AU  - James Sharman
AU  - Enrique Rodilla Sala
AU  - Piotr Jankowski
AU  - Maria Lorenza Muiesan
AU  - Cristina Giannattasio
AU  - Bernhard Hametner
AU  - Jose Maria Pascual
AU  - Robert Zweiker
AU  - Antonio Argyris
AU  - Anna Paini
AU  - Ian Wilkinson
AU  - Danuta Czarnecka
AU  - Massimo Salvetti
AU  - Alessandro Maloberti
AU  - Carmel McEniery
AU  - Yan Li
AU  - Janos Nemcsik
AU  - Giacomo Pucci
AU  - Cornelia Ablasser
AU  - Jacques Blacher
AU  - Alexandre Valleé
AU  - Alejandro de la Sierra
AU  - Yi Zhang
AU  - Hongwei Ji
AU  - Barry McDonnell
AU  - Marco Mota
AU  - Annelise Paiva
AU  - Andrea Brandao
AU  - Thomas Weber
PY  - 2020
DA  - 2020/02/15
TI  - P34 24-Hour Ambulatory Brachial Versus Aortic Systolic Blood Pressure: Relationship with Left Ventricular Mass Significantly Differs. Pooled Results from the International 24 Hour Aortic Blood Pressure Consortium (i24ABC)
JO  - Artery Research
SP  - S75
EP  - S75
VL  - 25
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191224.066
DO  - 10.2991/artres.k.191224.066
ID  - Wassertheurer2020
ER  -