Artery Research

Volume 16, Issue C, December 2016, Pages 77 - 77

12.3 24 HOUR AMBULATORY BLOOD PRESSURE MONITORING AND PULSE WAVE VELOCITY PATTERNS IN KENYAN ADOLESCENTS

Authors
Anthony Etyang1, 2, 3, 4
1KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya
2London School of Hygiene and Tropical Medicine, London, UK
3African Population and Health Research Centre, Nairobi, Kenya
4King’s College, London, UK
Available Online 24 November 2016.
DOI
10.1016/j.artres.2016.10.101How to use a DOI?
Abstract

Background: There are no data on ambulatory blood pressure monitoring (ABPM) and arterial stiffness parameters in sub-Saharan African children. We performed 24-hour ABPM and pulse wave velocity (PWV) measurements in adolescents living in 2 slums in Nairobi, Kenya.

Methods: We selected 1,100 11–17 year olds who from birth had been continuous residents of the Nairobi Urban Health and Demographic Surveillance System (NUHDSS) to participate in the study. Participants underwent anthropometric measurements (weight, height, mid-upper arm circumference [MUAC]) and answered questions on their socioeconomic status (SES). A clinic BP measurement was then taken using an automated Omron ™ M10-IT monitor (mean of 2 from 3 readings). Participants then underwent 24-hr ABPM and PWV measurement using an Arteriograph ™24 monitor.

Results: 500 (90%) of 558 children recruited between December 2015 and June 2016 had acceptable ABPM readings (≥ 20 daytime and ≥7 nighttime readings). Mean (SD) clinic BP, and 24 hour-ABPM values were 98(11) and 117(12) systolic and 63(8) and 64(7) mmHg diastolic respectively. Mean clinic PWV and 24 hour-PWV were 7.3(1.5) ms−1 and 7(0.8) ms−1respectively. In multivariate regression analyses age (p=0.004), BMI (p=0.033) and PWV (p<0.001) were strong independent predictors of 24-hour BP values. Blood indices (hemoglobin, white cell and platelet count), gender, MUAC and SES had no independent influence on 24hr BP and PWV.

Conclusions: These are to our knowledge the first 24hr ABPM and PWV data generated from sSA adolescents. Long-term cardiovascular outcome studies are needed to determine the predictive ability of ABPM and PWV measurements.

Open Access
This is an open access article distributed under the CC BY-NC license.

Journal
Artery Research
Volume-Issue
16 - C
Pages
77 - 77
Publication Date
2016/11/24
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2016.10.101How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Anthony Etyang
PY  - 2016
DA  - 2016/11/24
TI  - 12.3 24 HOUR AMBULATORY BLOOD PRESSURE MONITORING AND PULSE WAVE VELOCITY PATTERNS IN KENYAN ADOLESCENTS
JO  - Artery Research
SP  - 77
EP  - 77
VL  - 16
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2016.10.101
DO  - 10.1016/j.artres.2016.10.101
ID  - Etyang2016
ER  -