P126 THE ASSOCIATION OF THE INTEGRATED CENTRAL PRESSURE-STIFFNESS RISK SCORE WITH CARDIOVASCULAR MORTALITY IN HEMODIALYSIS PATIENTS

János Nemcsik; Dóra Batta; Ádám Tabák; Beáta Kőrösi; Orsolya Cseprekál; András Tislér

doi:10.1016/j.artres.2018.10.179

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Volume 24, Issue C, December 2018, Pages 116 - 116

P126 THE ASSOCIATION OF THE INTEGRATED CENTRAL PRESSURE-STIFFNESS RISK SCORE WITH CARDIOVASCULAR MORTALITY IN HEMODIALYSIS PATIENTS

Authors

János Nemcsik¹, Dóra Batta¹, Ádám Tabák², Beáta Kőrösi¹, Orsolya Cseprekál³, András Tislér²

¹Department of Family Medicine, Semmelweis University, Budapest, Hungary

²1st Department of Medicine, Semmelweis University, Budapest, Hungary

³Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

Available Online 4 December 2018.

DOI: 10.1016/j.artres.2018.10.179 How to use a DOI?
Abstract: Background: Our aim was to study the predictive power of ICPS risk categories on CV mortality in hemodialysis patients.

Methods: In our retrospective cohort study 91 patients were involved from two dialysis centers. Pulse Wave Velocity (PWV), central systolic blood pressure (cSBP) and and central pulse pressure (cPP) were measured with tonometric method, patients were followed for a median of 29.5 months and CV mortality was registered. Patients were classified into tertiles based on their PWV, cSBP and cPP values. After the analysis of the predictive values of the tertiles of the identical parameters, patients were scored. One score was given, when a patient had a third tertile value of cSBP or a second or third tertile value of PWV or cPP. Then the CV outcome was analyzed with Cox regression analysis of the groups of patients with different ICPS scores and three ICPS risk categories were defined: average (0-1 point), high (2 points) and very high (3 points).

Results: During follow-up 31 events occurred. After adjustment for multiple factors, compared with the average ICPS risk category group (n = 35; 38%), those, who were in the high risk group (n = 33; 30%) showed a tendency for significantly higher hazard ratio (HR) of CV mortality (HR = 2.62, 95% confidence interval (CI):0.82–8.43), while patients in the very high ICPS risk category (n = 23; 21%) had a markedly increased risk (HR = 10.03, CI:1.67–60.42).

Conclusions: The ICPS risk categories can help in the identification of hemodialysis patients with high CV risk.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 24 - C
Pages: 116 - 116
Publication Date: 2018/12/04
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2018.10.179 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - János Nemcsik
AU  - Dóra Batta
AU  - Ádám Tabák
AU  - Beáta Kőrösi
AU  - Orsolya Cseprekál
AU  - András Tislér
PY  - 2018
DA  - 2018/12/04
TI  - P126 THE ASSOCIATION OF THE INTEGRATED CENTRAL PRESSURE-STIFFNESS RISK SCORE WITH CARDIOVASCULAR MORTALITY IN HEMODIALYSIS PATIENTS
JO  - Artery Research
SP  - 116
EP  - 116
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.179
DO  - 10.1016/j.artres.2018.10.179
ID  - Nemcsik2018
ER  -

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